School of Chemistry and Biochemistry School of Chemistry and Biochemistry

Jean Gruenberg

Publications

2019

  • Gruenberg, J. (2019). Life in the lumen: the multivesicular endosome. Traffic (in press).
  • Moreau, D., Vacca, F., Vossio, S., Scott, C., Colaco, A., Paz Montoya, J., Ferguson, C., Damme, M., Moniatte, M., Parton, R.G., et al. (2019). Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice. EMBO Rep. e47055. doi: 10.15252/embr. 201847055.
  • Vacca, F., Vossio, S., Mercier, V., Moreau, D., Johnson, S., Scott, C.C., Paz Montoya, J., Moniatte, M., and Gruenberg, J. (2019). Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells. J Lipid Res. 60: :832-843. doi: 10.1194/jlr.

2018

  • Banach-Orlowska, M., Jastrzebski, K., Cendrowski, J., Maksymowicz, M., Wojciechowska, K., Korostynski, M., Moreau, D., Gruenberg, J., and Miaczynska, M. (2018). The topology of the lymphotoxin beta receptor that accumulates upon endolysosomal dysfunction dictates the NF-kappaB signaling outcome. J Cell Sci 131.
  • Lenoir, M., Ustunel, C., Rajesh, S., Kaur, J., Moreau, D., Gruenberg, J., and Overduin, M. (2018). Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting. Nature communications 9, 993. doi: 10.1038/s41467-018-03370-1
  • Scott, C.C., Vossio, S., Rougemont, J., and Gruenberg, J. (2018). TFAP2 transcription factors are regulators of lipid droplet biogenesis. Elife 7. pii: e36330. doi: 10.7554/eLife.36330.

2017

  • Muriel, O., Scott, C.C., Larios, J., Mercier, V., and Gruenberg, J. (2017). In Vitro Polymerization of F-actin on Early Endosomes. J Vis Exp, e55829.
  • Repnik, U., Distefano, M.B., Speth, M.T., Ng, M.Y.W., Progida, C., Hoflack, B., Gruenberg, J., and Griffiths, G. (2017). LLOMe does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes. J Cell Sci. 130: 3124-3140.
  • Moreau, D., and Gruenberg, J. (2016). Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs. Chimia (Aarau) 70, 878-882.

2016

  • Muriel, O., Tomas, A., Scott, C.C., and Gruenberg, J. (2016). Moesin and cortactin control actin-dependent multivesicular endosome biogenesis. Mol Biol Cell 27, 3305-3316.
  • Vacca, F., Scott, C.C., and Gruenberg, J. (2016). The late endosome. Encyclopedia of Cell Biology, Bradshaw, R A and Stahl, P D, eds 2, 201-210.
  • Wallabregue, A., Moreau, D., Sherin, P., Moneva Lorente, P., Jarolimova, Z., Bakker, E., Vauthey, E., Gruenberg, J., and Lacour, J. (2016). Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent Probe. J Am Chem Soc 138, 1752-1755.

2015

  • Overduin, M., S. Rajesh, J. Gruenberg, and M. Lenoir. (2015). Secondary structure and (1)H, (13)C, (15)N resonance assignments of the endosomal sorting protein sorting nexin 3. Biomol NMR Assign. 9:355-358.
  • Scott, C.C., S. Vossio, F. Vacca, B. Snijder, J. Larios, O. Schaad, N. Guex, D. Kuznetsov, O. Martin, M. Chambon, G. Turcatti, L. Pelkmans, and J. Gruenberg. (2015). Wnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis. EMBO Rep. 16:741-752.

2014

  • Bissig, C., and J. Gruenberg. (2014). ALIX and the multivesicular endosome: ALIX in Wonderland. Trends Cell Biol. 24:19-25.
  • Johnson, S., and J. Gruenberg. (2014). The pathway of VSV entry into cells In Biology and Pathogenesis of Rhabdo- and Filoviruses, A. Paitnak, and M. Whitt, eds. World Scientific Publishing Co.
  • Kufareva, I., Lenoir, M., Dancea, F., Sridhar, P., Raush, E., Bissig, C., Gruenberg, J., Abagyan, R., and Overduin, M. (2014). Discovery of novel membrane binding structures and functions. Biochemistry and Cell Biology 92:555-63.
  • Scott, C.C., F. Vacca, and J. Gruenberg. (2014). Endosome Maturation, Transport and Functions. Semin. Cell Dev. Biol.:http://dx.doi.org/10.1016/j.semcdb.2014.1003.1034.
  • van der Goot, F.G., and J. Gruenberg. (2014). Close encounter of the third kind: the ER meets endosomes at fission sites. Dev Cell. 31:673-674.

2013

  • Bissig, C., M. Lenoir, M.-C. Velluz, I. Kufareva, R. Abagyan, M. Overduin, and J. Gruenberg. 2013. Viral infection controlled by a novel calcium-dependent lipid-binding module in Alix. Dev . Cell. 4:364-373.
  • Bissig, C., and J. Gruenberg. 2013. Lipid sorting and multivesicular endosome biogenesis. Cold Spring Harb Perspect Biol. 5:a016816.
  • Chamoun, Z., F. Vacca, R.G. Parton, and J. Gruenberg. 2013. PNPLA3/adiponutrin functions in lipid droplet formation. Biol Cell. 105:219-233.

2012

  • Bissig, C., S. Johnson, and J. Gruenberg. 2012. Studying lipids involved in endocytosis. Meth. Cell Biol. 108:19-46.
  • Brankatschk, B., S.P. Wichert, S.D. Johnson, O. Schaad, M.J. Rossner, and J. Gruenberg. 2012. Regulation of the EGF Transcriptional Response by Endocytic Sorting. Science Signal. 5:ra21.
  • Falguières, T., J.D. Castle, and J. Gruenberg. 2012. Regulation of the MVB pathway by SCAMP3. Traffic. 13:131-142.
  • Gruenberg, J. 2012. An MBoC favorite: Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Molecular biology of the cell. 23:2402.
  • Pons, V., C. Ustunel, C. Rolland, E. Torti, R.G. Parton, and J. Gruenberg. 2012. SNX12 role in endosome membrane transport. PLoS ONE. 7:e38949. doi:38910.31371/journal.pone.0038949.
  • Snijder, B., R. Sacher, P. Ramo, P. Liberali, K. Mench, N. Wolfrum, L. Burleigh, C.C. Scott, M.H. Verheije, J. Mercer, S. Moese, T. Heger, K. Theusner, A. Jurgeit, D. Lamparter, G. Balistreri, M. Schelhaas, C.A. De Haan, V. Marjomaki, T. Hyypia, P.J. Rottier, B. Sodeik, M. Marsh, J. Gruenberg, A. Amara, U. Greber, A. Helenius, and L. Pelkmans. 2012. Single-cell analysis of population context advances RNAi screening at multiple levels. Mol Syst Biol. 8:579.

2011

  • Brankatschk, B., V. Pons, R.G. Parton, and J. Gruenberg. 2011. Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes. PLoS ONE. 6(7): e21771. doi:10.1371/journal.pone.0021771.
  • Laulagnier, K., N.L. Schieber, T. Maritzen, V. Haucke, R.G. Parton, and J. Gruenberg. 2011. Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes. Mol Biol Cell. 12:2068-2082.
  • Scott, C.C., C. Bissig, and J. Gruenberg. 2011. Duelling functions of the V-ATPase EMBO J. 30:413-415.
  • Scott, C.C., and J. Gruenberg. 2011. Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH. Bioessays. 33:103-110.

2010

  • Goursot, A., T. Mineva, C. Bissig, J. Gruenberg, and D.R. Salahub. 2010. Structure, dynamics, and energetics of lysobisphosphatidic acid (LBPA) isomers. J Phys Chem B. 114:15712-15720.

2009

  • Falguières, T., P.P. Luyet, and J. Gruenberg. 2009. Molecular assemblies and membrane domains in multivesicular endosomes. Experimental Cell Research. 315:1567-1573.
  • Gruenberg, J. 2009. Viruses and endosome membrane dynamics. Curr Opin Cell Biol. 21:582-588.
  • Morel, E., R.G. Parton, and J. Gruenberg. 2009. Annexin A2-dependent polymerization of actin mediates endosome biogenesis. Dev Cell. 16:445-457.
  • Morel, E., and J. Gruenberg. 2009. Annexin A2 binding to endosomes and functions in endosomal transport are regulated by tyrosine 23 phosphorylation. J Biol Chem. 284:1604-1611.

2008

  • Cataldo, A.M., P.M. Mathews, A.B. Boiteau, L.C. Hassinger, C.M. Peterhoff, Y. Jiang, K. Mullaney, R.L. Neve, J. Gruenberg, and R.A. Nixon. 2008. Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology. Accelerated Endocytosis Promotes Late Endocytic Defects. Am J Pathol.
  • Chevallier, J., Z. Chamoun, G. Jiang, G.D. Prestwich, N. Sakai, S. Matile, R.G. Parton, and J. Gruenberg. 2008. Lysobisphosphatidic acid controls endosomal cholesterol levels. J. Biol. Chem. 283:27871-27880.
  • Falguières, T., P.P. Luyet, C. Bissig, C.C. Scott, M.-C. Velluz, and J. Gruenberg. 2008. In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101. Mol Biol Cell. 19:4942-4955.
  • Kirkegaard-Sorensen, T., A. Roth, I. Moilanen, A. Zylicz, E. Schmitt, J. Gruenberg, C. Arenz, C. Garrido, K. Sandhoff, P.K.J. Kinnunen, J. Nylandsted, and M. Jaattela. 2008. Interaction between Hsp70 and bis( monoacylglycero) phosphate stabilizes lysosomes and promotes cell survival. APMIS. 116:436-437
  • Luyet, P.P., T. Falguières, V. Pons, A.K. Pattnaik, and J. Gruenberg. 2008. The ESCRT-I subunit Tsg101 controls endosome-to-cytosol release of viral RNA. Traffic. 9:2279-2290.
  • Mitrovic, S., H. Ben-Tekaya, E. Koegler, J. Gruenberg, and H.P. Hauri. 2008. The Cargo Receptors Surf4, Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)-53, and p25 Are Required to Maintain the Architecture of ERGIC and Golgi. Mol Biol Cell. 19:1976-1990.
  • Pons, V., P.-P. Luyet, E. Morel, L. Abrami, F.G. van der Goot, R.G. Parton, and J. Gruenberg. 2008. Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biology. 6:e214. doi:210.1371/journal.pbio.0060214.

2007

  • Felberbaum-Corti, M., E. Morel, V. Cavalli, F. Vilbois, and J. Gruenberg. 2007. The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis. PLoS ONE. 2:e1144.
  • Luyet, P.P., T. Falguières, V. Pons, and J. Gruenberg. 2007. Endosomal Membrane Dynamics. J. Oral Biosci. 49:01-17.
  • Morel, E., and J. Gruenberg. 2007. The p11/S100A10 light chain of annexin A2 is dispensable for annexin A2 association to endosomes and functions in endosomal transport. PLoS ONE. 2:e1118.
  • Sbrissa, D., O.C. Ikonomov, Z. Fu, T. Ijuin, J. Gruenberg, T. Takenawa, and A. Shisheva. 2007. Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex. J Biol Chem. 282:23878-23891.
  • Sobo, K., I. Le Blanc, P.P. Luyet, M. Fivaz, C. Ferguson, R.G. Parton, J. Gruenberg, and F.G. van der Goot. 2007b. Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking. PLoS ONE. 2:e851.
  • Sobo, K., J. Chevallier, R.G. Parton, J. Gruenberg, and F.G. van der Goot. 2007a. Diversity of raft-like domains in late endosomes. PLoS ONE. 2:e391.

2006

  • Brissoni, B., L. Agostini, M. Kropf, F. Martinon, V. Swoboda, S. Lippens, H. Everett, N. Aebi, S. Janssens, E. Meylan, M. Felberbaum-Corti, H. Hirling, J. Gruenberg, J. Tschopp, and K. Burns. 2006. Intracellular trafficking of interleukin-1 receptor I requires Tollip. Curr Biol. 16:2265-2270.
  • Chevallier, J., and J. Gruenberg. 2006. Lipid Membrane Domains in Endosomes. In "Endosomes" (Dikic I, ed). Georgetown, TX: Landes Bioscience.
  • Gruenberg, J., and F.G. van der Goot. 2006a. Mechanisms of pathogen entry through the endosomal compartments. Nat Rev Mol Cell Biol. 7:495-504.
  • Gruenberg, J., and F.G. van der Goot. 2006b. Toxoplasma: guess who's coming to dinner. Cell. 125:226-228.
  • van der Goot, F.G., and J. Gruenberg. 2006. Intra-endosomal membrane traffic. Trends Cell Biol. 16:514-521.

2005

  • Alcon-LePoder, S., M.T. Drouet, P. Roux, M.P. Frenkiel, M. Arborio, A.M. Durand-Schneider, M. Maurice, I. Le Blanc, J. Gruenberg, and M. Flamand. 2005. The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity. J Virol. 79:11403-11411.
  • Felberbaum-Corti, M., V. Cavalli, and J. Gruenberg. 2005. Capture of the small GTPase Rab5 by GDI: regulation by p38 MAP kinase. Methods Enzymol. 403:367-381.
  • Gagescu, R., and J. Gruenberg. 2005. Immuno-isolation of organelles using magnetic solid supports. in "Cell Biology, Four-Volume Set - A Laboratory Handbook(Volume 1-4)" Third Edition (by J. Celis, K. Simons, J.V. Small, T. Hunter and D. Shotton, eds) Vol 2:27-31.
  • Jiang, G., Y. Xu, T. Falguieres, J. Gruenberg, and G.D. Prestwich. 2005. Concise synthesis of ether analogues of lysobisphosphatidic acid. Org Lett. 7:3837-3840.
  • Le Blanc, I., P.P. Luyet, V. Pons, C. Ferguson, N. Emans, A. Petiot, N. Mayran, N. Demaurex, J. Faure, R. Sadoul, R.G. Parton, and J. Gruenberg. 2005. Endosome-to-cytosol transport of viral nucleocapsids. Nat Cell Biol. 7:653-664.
  • Luyet, P.P., and J. Gruenberg. 2005. [Endocytosis: the Trojan Horse of viral infection]. Med Sci (Paris). 21:909-910.
  • Robinson, L.J., and J. Gruenberg. 2005. Assays measuring membrane transport in the endocytic pathway. in "Cell Biology, Four-Volume Set - A Laboratory Handbook(Volume 1-4)" Third Edition (by J. Celis, K. Simons, J.V. Small, T. Hunter and D. Shotton, eds) Vol 2:201-208.

2004

  • Aniento, F., and J. Gruenberg. 2004. Subcellular fractionation of tissue culture cells. Curr Protoc Protein Sci. Chapter 4:Unit 4 3.
  • Faure, J., R. Stalder, C. Borel, K. Sobo, V. Piguet, N. Demaurex, J. Gruenberg, and D. Trono. 2004. ARF1 regulates Nef-induced CD4 degradation. Curr Biol. 14:1056-1064.
  • Felberbaum-Corti, M., R. Gagescu, and J. Gruenberg. 2004. Membrane Trafficking in the Endocytic Pathway of Eukaryotic Cell. in "Cellular Microbiology" 2nd Edition (P. Cossart, P. Boquet, S. Normark & R. Rappuoli, Eds). American Society for Microbiology Press.
  • Gruenberg, J., and H. Stenmark. 2004. The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol. 5:317-323.
  • Matsuo, H., J. Chevallier, N. Mayran, I. Le Blanc, C. Ferguson, J. Fauré, N. Sartori-Blanc, S. Matile, J. Dubochet, R. Sadoul, R.G. Parton, F. Vilbois, and J. Gruenberg. 2004. Role of LBPA and Alix in multivesicular liposome formation and endosome organization. Science. 303:531-534.
  • Vieira, O.V., R.E. Harrison, C.C. Scott, H. Stenmark, D. Alexander, J. Liu, J. Gruenberg, A.D. Schreiber, and S. Grinstein. 2004. Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Mol Cell Biol. 24:4593-4604.

2003

  • Aniento, F., and J. Gruenberg. 2003. Subcellular fractionation of tissue culture cells. Curr Protoc Immunol. Chapter 8:Unit 8 1C.
  • Emery, G., R.G. Parton, M. Rojo, and J. Gruenberg. 2003. The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics. J Cell Sci. 116:4821-4832.
  • Felberbaum-Corti, M., F.G. Van Der Goot, and J. Gruenberg. 2003. Sliding doors: clathrin-coated pits or caveolae? Nat Cell Biol. 5:382-384.
  • Gruenberg, J. 2003. Lipids in endocytic membrane transport and sorting. Curr Opin Cell Biol. 15:382-388.
  • Mayran, N., R.G. Parton, and J. Gruenberg. 2003. Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. Embo J. 22:3242-3253.
  • Petiot, A., J. Faure, H. Stenmark, and J. Gruenberg. 2003. PI3P signaling regulates receptor sorting but not transport in the endosomal pathway. J Cell Biol. 162:971-979.
  • Vieira, O.V., C. Bucci, R.E. Harrison, W.S. Trimble, L. Lanzetti, J. Gruenberg, A.D. Schreiber, P.D. Stahl, and S. Grinstein. 2003. Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol. 23:2501-2514.

2002

  • Felberbaum-Corti, M., and J. Gruenberg. 2002. Signaling from the far side. Mol Cell. 10:1259-1260.
  • Incardona, J.P., J. Gruenberg, and H. Roelink. 2002. Sonic hedgehog induces the segregation of patched and smoothened in endosomes. Curr Biol. 12:983-995.
  • Kobayashi, T., M.H. Beuchat, J. Chevallier, A. Makino, N. Mayran, J.M. Escola, C. Lebrand, P. Cosson, and J. Gruenberg. 2002. Separation and characterization of late endosomal membrane domains. J Biol Chem. 277:32157-32164.
  • Lebrand, C., M. Corti, H. Goodson, P. Cosson, V. Cavalli, N. Mayran, J. Faure, and J. Gruenberg. 2002. Late endosome motility depends on lipids via the small GTPase Rab7. Embo J. 21:1289-1300.
  • Sorice, M., D. Ferro, R. Misasi, V. Pittoni, A. Longo, A. Circella, T. Garofalo, R. Gradini, F. Violi, J. Gruenberg, and G. Valesini. 2002. Evidence for anticoagulant activity and beta2-GPI accumulation in late endosomes of endothelial cells induced by anti-LBPA antibodies. Thromb Haemost. 87:735-741.
  • van der Goot, F.G., and J. Gruenberg. 2002. Oiling the wheels of the endocytic pathway. Trends Cell Biol. 12:296-299.

2001

  • Alpy, F., M.E. Stoeckel, A. Dierich, J.M. Escola, C. Wendling, M.P. Chenard, M.T. Vanier, J. Gruenberg, C. Tomasetto, and M.C. Rio. 2001. The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein. J Biol Chem. 276:4261-4269.
  • Cavalli, V., F. Vilbois, M. Corti, M.J. Marcote, K. Tamura, M. Karin, S. Arkinstall, and J. Gruenberg. 2001b. The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex. Mol Cell. 7:421-432.
  • Cavalli, V., M. Corti, and J. Gruenberg. 2001a. Endocytosis and signaling cascades: a close encounter. FEBS Lett. 498:190-196.
  • Dunoyer-Geindre, S., E.K. Kruithof, B. Galve-de Rochemonteix, C. Rosnoblet, J. Gruenberg, G. Reber, and P. de Moerloose. 2001. Localization of beta2-glycoprotein 1 in late endosomes of human endothelial cells. Thromb Haemost. 85:903-907.
  • Fratti, R.A., J.M. Backer, J. Gruenberg, S. Corvera, and V. Deretic. 2001. Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J Cell Biol. 154:631-644.
  • Gruenberg, J. 2001. The endocytic pathway: a mosaic of domains. Nat Rev Mol Cell Biol. 2:721-730.

2000

  • Bao, J., I. Alroy, H. Waterman, E.D. Schejter, C. Brodie, J. Gruenberg, and Y. Yarden. 2000. Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome. J Biol Chem. 275:26178-26186.
  • Chevallier, J., N. Sakai, F. Robert, T. Kobayashi, J. Gruenberg, and S. Matile. 2000. Rapid access to synthetic lysobisphosphatidic acids using P(III) chemistry. Org Lett. 2:1859-1861.
  • Emery, G., M. Rojo, and J. Gruenberg. 2000. Coupled transport of p24 family members. J Cell Sci. 113 ( Pt 13):2507-2516.
  • Gagescu, R., J. Gruenberg, and E. Smythe. 2000b. Membrane dynamics in endocytosis: structure--function relationship. Traffic. 1:84-88.
  • Gagescu, R., N. Demaurex, R.G. Parton, W. Hunziker, L.A. Huber, and J. Gruenberg. 2000a. The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components. Mol Biol Cell. 11:2775-2791.
  • Galve-de Rochemonteix, B., T. Kobayashi, C. Rosnoblet, M. Lindsay, R.G. Parton, G. Reber, E. de Maistre, D. Wahl, E.K. Kruithof, J. Gruenberg, and P. de Moerloose. 2000. Interaction of anti-phospholipid antibodies with late endosomes of human endothelial cells. Arterioscler Thromb Vasc Biol. 20:563-574.
  • Gu, F., and J. Gruenberg. 2000. ARF1 regulates pH-dependent COP functions in the early endocytic pathway. J Biol Chem. 275:8154-8160.
  • Huber, L.A., I. Fialka, K. Paiha, W. Hunziker, D.B. Sacks, M. Bahler, M. Way, R. Gagescu, and J. Gruenberg. 2000. Both calmodulin and the unconventional myosin Myr4 regulate membrane trafficking along the recycling pathway of MDCK cells. Traffic. 1:494-503.
  • Juuti-Uusitalo, K., K.J. Airenne, A. Laukkanen, E.L. Punnonen, V.M. Olkkonen, J. Gruenberg, M. Kulomaa, and V. Marjomaki. 2000. Selective targeting of avidin/mannose 6-phosphate receptor chimeras to early or late endosomes. Eur J Cell Biol. 79:458-468.
  • Kobayashi, T., U.M. Vischer, C. Rosnoblet, C. Lebrand, M. Lindsay, R.G. Parton, E.K. Kruithof, and J. Gruenberg. 2000. The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells. Mol Biol Cell. 11:1829-1843.
  • Rojo, M., G. Emery, V. Marjomaki, A.W. McDowall, R.G. Parton, and J. Gruenberg. 2000. The transmembrane protein p23 contributes to the organization of the Golgi apparatus. J Cell Sci. 113 ( Pt 6):1043-1057.
  • Simons, K., and J. Gruenberg. 2000. Jamming the endosomal system: lipid rafts and lysosomal storage diseases. Trends Cell Biol. 10:459-462.

1999

  • Gu, F., and J. Gruenberg. 1999. Biogenesis of transport intermediates in the endocytic pathway. FEBS Lett. 452:61-66.
  • Kobayashi, T., M.H. Beuchat, M. Lindsay, S. Frias, R.D. Palmiter, H. Sakuraba, R.G. Parton, and J. Gruenberg. 1999. Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport. Nat Cell Biol. 1:113-118.
  • Kobayashi, T., and J. Gruenberg. 1999. [Cell biology of lysobisphosphatidic acid]. Tanpakushitsu Kakusan Koso. 44:1181-1186.
  • Piguet, V., F. Gu, M. Foti, N. Demaurex, J. Gruenberg, J.L. Carpentier, and D. Trono. 1999. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. Cell. 97:63-73.

1998

  • Kobayashi, T., E. Stang, K.S. Fang, P. de Moerloose, R.G. Parton, and J. Gruenberg. 1998b. A lipid associated with the antiphospholipid syndrome regulates endosome structure and function. Nature. 392:193-197.
  • Kobayashi, T., F. Gu, and J. Gruenberg. 1998a. Lipids, lipid domains and lipid-protein interactions in endocytic membrane traffic. Semin Cell Dev Biol. 9:517-526.

1997

  • Gu, F., F. Aniento, R.G. Parton, and J. Gruenberg. 1997. Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes. J Cell Biol. 139:1183-1195.
  • Harder, T., R. Kellner, R.G. Parton, and J. Gruenberg. 1997. Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol. Mol Biol Cell. 8:533-545.
  • Robinson, L.J., F. Aniento, and J. Gruenberg. 1997. NSF is required for transport from early to late endosomes. J Cell Sci. 110 ( Pt 17):2079-2087.
  • Rojo, M., N. Budin, R. Kellner, and J. Gruenberg. 1997a. Generation of proteoliposomes from subcellular fractions. Electrophoresis. 18:2620-2628.
  • Rojo, M., R. Pepperkok, G. Emery, R. Kellner, E. Stang, R.G. Parton, and J. Gruenberg. 1997b. Involvement of the transmembrane protein p23 in biosynthetic protein transport. J Cell Biol. 139:1119-1135.

1996

  • Aniento, F., F. Gu, R.G. Parton, and J. Gruenberg. 1996. An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes. J Cell Biol. 133:29-41.
  • Huber, L.A., C. Pasquali, R. Gagescu, A. Zuk, J. Gruenberg, and K.S. Matlin. 1996. Endosomal fractions from viral K-ras-transformed MDCK cells reveal transformation specific changes on two-dimensional gel maps. Electrophoresis. 17:1734-1740.

1995

  • Aniento, F., and J. Gruenberg. 1995. Membrane transport from early to late endosomes. Cold Spring Harb Symp Quant Biol. 60:205-209.
  • Gruenberg, J., and F.R. Maxfield. 1995. Membrane transport in the endocytic pathway. Curr Opin Cell Biol. 7:552-563.
  • Gruenberg, J., and T.E. Kreis. 1995. Membranes and sorting. Curr Opin Cell Biol. 7:519-522.

1994

  • Clague, M.J., S. Urbe, F. Aniento, and J. Gruenberg. 1994. Vacuolar ATPase activity is required for endosomal carrier vesicle formation. J Biol Chem. 269:21-24.
  • Marjomaki, V., V. Ritamaki, and J. Gruenberg. 1994. Isoproterenol-induced redistribution of endosomes in cardiac myocytes. Eur J Cell Biol. 65:1-13.
  • Steele-Mortimer, O., M.J. Clague, L.A. Huber, P. Chavrier, J. Gruenberg, and J.P. Gorvel. 1994. The N-terminal domain of a rab protein is involved in membrane-membrane recognition and/or fusion. Embo J. 13:34-41.
  • Stenmark, H., R.G. Parton, O. Steele-Mortimer, A. Lutcke, J. Gruenberg, and M. Zerial. 1994. Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. Embo J. 13:1287-1296.

1993

  • Aniento, F., N. Emans, G. Griffiths, and J. Gruenberg. 1993. Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J Cell Biol. 123:1373-1387.
  • Emans, N., J.P. Gorvel, C. Walter, V. Gerke, R. Kellner, G. Griffiths, and J. Gruenberg. 1993. Annexin II is a major component of fusogenic endosomal vesicles. J Cell Biol. 120:1357-1369.
  • Steele-Mortimer, O., J. Gruenberg, and M.J. Clague. 1993. Phosphorylation of GDI and membrane cycling of rab proteins. FEBS Lett. 329:313-318.

1992

  • Gruenberg, J., and M.J. Clague. 1992. Regulation of intracellular membrane transport. Curr Opin Cell Biol. 4:593-599.
  • Kurzchalia, T.V., J.P. Gorvel, P. Dupree, R. Parton, R. Kellner, T. Houthaeve, J. Gruenberg, and K. Simons. 1992. Interactions of rab5 with cytosolic proteins. J Biol Chem. 267:18419-18423.
  • Parton, R.G., P. Schrotz, C. Bucci, and J. Gruenberg. 1992. Plasticity of early endosomes. J Cell Sci. 103 ( Pt 2):335-348.
  • Thomas, L., P.R. Clarke, M. Pagano, and J. Gruenberg. 1992. Inhibition of membrane fusion in vitro via cyclin B but not cyclin A. J Biol Chem. 267:6183-6187.

1991

  • Chavrier, P., J.P. Gorvel, E. Stelzer, K. Simons, J. Gruenberg, and M. Zerial. 1991. Hypervariable C-terminal domain of rab proteins acts as a targeting signal. Nature. 353:769-772.
  • Gorvel, J.P., P. Chavrier, M. Zerial, and J. Gruenberg. 1991. rab5 controls early endosome fusion in vitro. Cell. 64:915-925.
  • Gruenberg, J. 1991. In vitro studies of endocytic membrane traffic. Infection. 19 Suppl 4:S210-215.

1990

  • Bomsel, M., R. Parton, S.A. Kuznetsov, T.A. Schroer, and J. Gruenberg. 1990. Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells. Cell. 62:719-731.

1989

  • Bomsel, M., K. Prydz, R.G. Parton, J. Gruenberg, and K. Simons. 1989. Endocytosis in filter-grown Madin-Darby canine kidney cells. J Cell Biol. 109:3243-3258.
  • Gruenberg, J., G. Griffiths, and K.E. Howell. 1989. Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro. J Cell Biol. 108:1301-1316.
  • Gruenberg, J., and K.E. Howell. 1989. Membrane traffic in endocytosis: insights from cell-free assays. Annu Rev Cell Biol. 5:453-481.
  • Howell, K.E., E. Devaney, and J. Gruenberg. 1989a. Subcellular fractionation of tissue culture cells. Trends Biochem Sci. 14:44-47.
  • Howell, K.E., R. Schmid, J. Ugelstad, and J. Gruenberg. 1989b. Immunoisolation using magnetic solid supports: subcellular fractionation for cell-free functional studies. Methods Cell Biol. 31:265-292.
  • McDowall, A., J. Gruenberg, K. Romisch, and G. Griffiths. 1989. The structure of organelles of the endocytic pathway in hydrated cryosections of cultured cells. Eur J Cell Biol. 49:281-294.
  • Tuomikoski, T., M.A. Felix, M. Doree, and J. Gruenberg. 1989. Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2. Nature. 342:942-945.

1988

  • Howell, K.E., J. Gruenberg, A. Ito, and G.E. Palade. 1988. Immuno-isolation of subcellular components. Prog Clin Biol Res. 270:77-90.
  • Gruenberg, J., and K.E. Howell. 1988. Fusion in the endocytic pathway reconstituted in a cell-free system using immuno-isolated fractions. Prog Clin Biol Res. 270:317-331.

1987

  • Davoust, J., J. Gruenberg, and K.E. Howell. 1987. Two threshold values of low pH block endocytosis at different stages. Embo J. 6:3601-3609.
  • Gruenberg, J., and K.E. Howell. 1987. An internalized transmembrane protein resides in a fusion-competent endosome for less than 5 minutes. Proc Natl Acad Sci U S A. 84:5758-5762.
  • Masur, S.K., J. Gruenberg, and K.E. Howell. 1987. Endosomal compartment of toad bladder epithelium. Am J Physiol. 252:C115-120.

1986

  • Allred, D.R., J.E. Gruenberg, and I.W. Sherman. 1986. Dynamic rearrangements of erythrocyte membrane internal architecture induced by infection with Plasmodium falciparum. J Cell Sci. 81:1-16.
  • Gruenberg, J., and K.E. Howell. 1986. Reconstitution of vesicle fusions occurring in endocytosis with a cell-free system. Embo J. 5:3091-3101.

1985

  • Gruenberg, J., and K.E. Howell. 1985. Immuno-isolation of vesicles using antigenic sites either located on the cytoplasmic or the exoplasmic domain of an implanted viral protein. A quantitative analysis. Eur J Cell Biol. 38:312-321.

1983

  • Gruenberg, J., D.R. Allred, and I.W. Sherman. 1983. Scanning electron microscope-analysis of the protrusions (knobs) present on the surface of Plasmodium falciparum-infected erythrocytes. J Cell Biol. 97:795-802.
  • Gruenberg, J., and I.W. Sherman. 1983. Isolation and characterization of the plasma membrane of human erythrocytes infected with the malarial parasite Plasmodium falciparum. Proc Natl Acad Sci U S A. 80:1087-1091.

1980

  • Gruenberg, J., B. Schwendimann, P.R. Sharma, and J. Deshusses. 1980. Role of glycerol permeation in the bloodstream form of Trypanosoma brucei. J Protozool. 27:484-491.

1979

  • Gruenberg, J., D. Coral, A.L. Knupfer, and J. Deshusses. 1979. Interactions of liposomes with Trypanosoma brucei plasma membrane. Biochem Biophys Res Commun. 88:1173-1179.

1978

  • Gruenberg, J., P.R. Sharma, and J. Deshusses. 1978. D-Glucose transport in Trypanosoma brucei. D-Glucose transport is the rate-limiting step of its metabolism. Eur J Biochem. 89:461-469.