I am currently a "chef de clinique scientifique" (50% clinical, 50% research) within the Division of Hematology, Department of Oncology, HUG. After my MD from University of Genoa, Italy, I obtained a MSc in Immunology form Pasteur Institute/University of Paris-VII and a PhD in Immunology form University of Paris-Sud. I then did my postgraduate training in Internal Medicine and Hematology at HUG. In 2016, I joined the lab of Pr. RS Negrin at Stanford University as a postdoctoral fellow. I came back in 2020 hosted for my research activity in the lab of Pr. J. Tamburini at CRTOH. I am member of the Working group for Cellular Therapies of the SAKK and the SBST and of the Swiss Board on Multiple Myeloma CAR T cells. I am co-chair of the Immune monitoring subcommittee of the Cellular Therapy & Immunobiology Working Party(CTIWP) of the European Society for Blood and Marrow Transplantation (EBMT). Within the CRTOH, I have several established collaborations (Pr. Jérôme Tamburini, Pr. Camilla Jandus) around acute myeloid leukemia.

My clinical work is mainly focused on Chimeric Antigen Receptor (CAR) T cells and allogeneic hematopoietic stem cell transplantation (HSCT). I am the medical coordinator of the CAR T cell program that we started at HUG in 2021. My main research interest is the development of immune-effector and immune-regulatory allogeneic cellular therapies for treatment of hematologic malignancies and graft-versus-host-disease (GvHD) respectively. In addition, I study mechanisms of immune-reconstitution after allogeneic HSCT and CAR T cell therapy with a particular focus on the identification of biomarkers for immune-monitoring. We combine in vitro studies with ex vivo analysis on clinical samples obtained from patients from the allogeneic HSCT program led by Pr. Yves Chalandon. In addition, I have several local (Pr. Laurent Kaiser, HUG), national (Pr. Francesco Bertoni, IOR, Bellinzona) and international (Pr. Antonio Pierini, University of Perugia, Italy; Pr. Robert S. Negrin, Stanford University, USA) collaborations around these research topics.