Towards a national strategy for digital pathology in Switzerland.

Janowczyk A, Baumhoer D, Dirnhofer S, Grobholz R, Kipar A, de Leval L, Merkler D, Michielin O, Moch H, Perren A, Rottenberg S, Rubbia-Brandt L, Rubin MA, Sempoux C, Tolnay M, Zlobec I, Koelzer VH; Swiss Digital Pathology Consortium (SDiPath).

Virchows Arch. 2022 Oct;481(4):647-652. doi: 10.1007/s00428-022-03345-0. Epub 2022 May 27.

PMID: 35622144

Special Issue "IL-1 family cytokines in host defense, inflammation and cancer".

Palmer G, Gabay C.

Cytokine. 2022 Oct;158:156010. doi: 10.1016/j.cyto.2022.156010. Epub 2022 Aug 24.

PMID: 36029747 No abstract available.

Mazzotti reaction: Ivermectin-associated polyarthritis after delayed scabies treatment. Case report and review of the literature.

Antonio JA, Rollason V, Musumeci S, Finckh A, Lazarou I, Laffitte E, Nendaz M, Serratrice J, Coen M.

Therapie. 2022 Sep-Oct;77(5):612-616. doi: 10.1016/j.therap.2021.10.001. Epub 2021 Oct 14.

PMID: 34732299 Review. No abstract available.

Optimizing the Live Attenuated Influenza A Vaccine Backbone for High-Risk Patient Groups.

Bonifacio JPPL, Williams N, Garnier L, Hugues S, Schmolke M, Mazel-Sanchez B.

J Virol. 2022 Oct 3:e0087122. doi: 10.1128/jvi.00871-22. Online ahead of print.

PMID: 36190240

Autoantibodies against apolipoprotein A-1 after COVID-19 predict symptoms persistence.

L'Huillier AG, Pagano S, Baggio S, Meyer B, Andrey DO, Nehme M, Guessous I, Eberhardt CS, Huttner A, Posfay-Barbe KM, Yerly S, Siegrist CA, Kaiser L, Vuilleumier N.

Eur J Clin Invest. 2022 Oct;52(10):e13818. doi: 10.1111/eci.13818. Epub 2022 Jun 2.

PMID: 35598178 Free PMC article.

Periodontitis and peri-implantitis in elderly people experiencing institutional and hospital confinement.

Müller F, Srinivasan M, Krause KH, Schimmel M.

Periodontol 2000. 2022 Oct;90(1):138-145. doi: 10.1111/prd.12454. Epub 2022 Aug 2.

PMID: 35916869 Review.

Global epidemiology of rheumatoid arthritis.

Finckh A, Gilbert B, Hodkinson B, Bae SC, Thomas R, Deane KD, Alpizar-Rodriguez D, Lauper K.

Nat Rev Rheumatol. 2022 Oct;18(10):591-602. doi: 10.1038/s41584-022-00827-y. Epub 2022 Sep 6.

PMID: 36068354 Review.

Impact of COVID-19 on the liver and on the care of patients with chronic liver disease, hepatobiliary cancer, and liver transplantation: An updated EASL position paper.

Marjot T, Eberhardt CS, Boettler T, Belli LS, Berenguer M, Buti M, Jalan R, Mondelli MU, Moreau R, Shouval D, Berg T, Cornberg M.

J Hepatol. 2022 Oct;77(4):1161-1197. doi: 10.1016/j.jhep.2022.07.008. Epub 2022 Jul 20.

PMID: 35868584 Free PMC article.

Synergistic prostaglandin E synthesis by myeloid and endothelial cells promotes fetal hematopoietic stem cell expansion in vertebrates.

Cacialli P, Mailhe MP, Wagner I, Merkler D, Golub R, Bertrand JY.

EMBO J. 2022 Oct 4;41(19):e108536. doi: 10.15252/embj.2021108536. Epub 2022 Aug 4.

PMID: 35924455

Effectiveness of TNF-inhibitors, abatacept, IL6-inhibitors and JAK-inhibitors in 31 846 patients with rheumatoid arthritis in 19 registers from the 'JAK-pot' collaboration.

Lauper K, Iudici M, Mongin D, Bergstra SA, Choquette D, Codreanu C, Cordtz R, De Cock D, Dreyer L, Elkayam O, Hauge EM, Huschek D, Hyrich KL, Iannone F, Inanc N, Kearsley-Fleet L, Kristianslund EK, Kvien TK, Leeb BF, Lukina G, Nordström DC, Pavelka K, Pombo-Suarez M, Rotar Z, Santos MJ, Strangfeld A, Verschueren P, Courvoisier DS, Finckh A.

Ann Rheum Dis. 2022 Oct;81(10):1358-1366. doi: 10.1136/annrheumdis-2022-222586. Epub 2022 Jun 15.

PMID: 35705376 Free PMC article.

Control of lymph node activity by direct local innervation.

De Virgiliis F, Oliva VM, Kizil B, Scheiermann C.

Trends Neurosci. 2022 Sep;45(9):704-712. doi: 10.1016/j.tins.2022.06.006. Epub 2022 Jul 9.

PMID: 35820971 Review.

Patients with elevated basal tryptase serum levels should be tested for hereditary alpha-tryptasemia.

Spoerl D, Docquier M, Coattrenec Y, Seebach JD.

Eur Ann Allergy Clin Immunol. 2022 Sep;54(5):242-244. doi: 10.23822/EurAnnACI.1764-1489.220. Epub 2021 Jul 11.

PMID: 34124865 No abstract available.

Smc5/6 silences episomal transcription by a three-step function.

Abdul F, Diman A, Baechler B, Ramakrishnan D, Kornyeyev D, Beran RK, Fletcher SP, Strubin M.

Nat Struct Mol Biol. 2022 Sep;29(9):922-931. doi: 10.1038/s41594-022-00829-0. Epub 2022 Sep 12.

PMID: 36097294

Single-cell immune repertoire sequencing of B and T cells in murine models of infection and autoimmunity.

Shlesinger D, Hong KL, Shammas G, Page N, Sandu I, Agrafiotis A, Kreiner V, Fonta N, Vincenti I, Wagner I, Piccinno M, Mariotte A, Klimek B, Dizerens R, Manero-Carranza M, Kuhn R, Ehling R, Frei L, Khodaverdi K, Panetti C, Joller N, Oxenius A, Merkler D, Reddy ST, Yermanos A.

Genes Immun. 2022 Sep;23(6):183-195. doi: 10.1038/s41435-022-00180-w. Epub 2022 Aug 26.

PMID: 36028771 Free PMC article.

Management of hand osteoarthritis: from an US evidence-based medicine guideline to a European patient-centric approach.

Fuggle N, Bere N, Bruyère O, Rosa MM, Prieto Yerro MC, Dennison E, Dincer F, Gabay C, Haugen IK, Herrero-Beaumont G, Hiligsmann M, Hochberg MC, Laslop A, Matijevic R, Maheu E, Migliore A, Pelletier JP, Radermecker RP, Rannou F, Uebelhart B, Uebelhart D, Veronese N, Vlaskovska M, Rizzoli R, Mobasheri A, Cooper C, Reginster JY.

Aging Clin Exp Res. 2022 Sep;34(9):1985-1995. doi: 10.1007/s40520-022-02176-y. Epub 2022 Jul 21.

PMID: 35864304 Free PMC article. Review.

The Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: predicting clinical arthritis development.

van Boheemen L, Ter Wee MM, Falahee M, Filer A, van Beers-Tas M, Finckh A, Hensvold A, Raza K, van Schaardenburg D.

Scand J Rheumatol. 2022 Sep 29:1-8. doi: 10.1080/03009742.2022.2116806. Online ahead of print.

PMID: 36174085

Conoid extrusion regulates glideosome assembly to control motility and invasion in Apicomplexa.

Dos Santos Pacheco N, Brusini L, Haase R, Tosetti N, Maco B, Brochet M, Vadas O, Soldati-Favre D.

Nat Microbiol. 2022 Sep 15. doi: 10.1038/s41564-022-01212-x. Online ahead of print.

PMID: 36109645

Comparative Effectiveness of Guselkumab in Psoriatic Arthritis: Updates to a Systematic Literature Review and Network Meta-Analysis.

Mease PJ, McInnes IB, Tam LS, Rajalingam R, Peterson S, Hassan F, Chakravarty SD, Contré C, Armstrong A, Boehncke WH, Ritchlin C.

Rheumatology (Oxford). 2022 Sep 14:keac500. doi: 10.1093/rheumatology/keac500. Online ahead of print.

PMID: 36102818

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12.

Garris CS, Arlauckas SP, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, Pierce RH, Le MH, Algazi AP, Daud AI, Pai SI, Zippelius A, Weissleder R, Pittet MJ.

Immunity. 2022 Sep 13;55(9):1749. doi: 10.1016/j.immuni.2022.07.021.

PMID: 36103861 No abstract available.

T Cell Receptor Sequencing Reveals Reduced Clonal Breadth of T Cell Responses against SARS-CoV-2 after Natural Infection and Vaccination in Allogeneic Hematopoietic Stem Cell Transplant Recipients.

Pradier A, Mamez AC, Stephan C, Giannotti F, Masouridi-Levrat S, Wang S, Morin S, Neofytos D, Vu DL, Melotti A, Arm I, Eberhardt CS, Tamburini J, Kaiser L, Chalandon Y, Simonetta F.

Ann Oncol. 2022 Sep 15:S0923-7534(22)04144-8. doi: 10.1016/j.annonc.2022.09.153. Online ahead of print.

PMID: 36116692 Free PMC article. No abstract available.

Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling.

Soomro M, Stadler M, Dand N, Bluett J, Jadon D, Jalali-Najafabadi F, Duckworth M, Ho P, Marzo-Ortega H, Helliwell PS, Ryan AW, Kane D, Korendowych E, Simpson MA, Packham J, McManus R, Gabay C, Lamacchia C, Nissen MJ, Brown MA, Verstappen SMM, Van Staa T, Barker JN, Smith CH; BADBIR Study Group; BSTOP study group, FitzGerald O, McHugh N, Warren RB, Bowes J, Barton A.

Arthritis Rheumatol. 2022 Sep;74(9):1535-1543. doi: 10.1002/art.42154. Epub 2022 Aug 4.

PMID: 35507331

Development and in vivo validation of small interfering RNAs targeting NOX3 to prevent sensorineural hearing loss.

Nacher-Soler G, Marteyn A, Barenzung N, Sgroi S, Krause KH, Senn P, Rousset F.

Front Neurol. 2022 Sep 16;13:993017. doi: 10.3389/fneur.2022.993017. eCollection 2022.

PMID: 36188374 Free PMC article.

Monocytosis in the acute phase of SARS-CoV-2 infection predicts the presence of anosognosia for cognitive deficits in the chronic phase.

Nuber-Champier A, Voruz P, Jacot de Alcântara I, Breville G, Allali G, Lalive PH, Assal F, Péron JA.

Brain Behav Immun Health. 2022 Dec;26:100511. doi: 10.1016/j.bbih.2022.100511. Epub 2022 Sep 16.

PMID: 36128057 Free PMC article.

Randomized double-blind clinical study in patients with COVID-19 to evaluate the safety and efficacy of a phytomedicine (P2Et).

Urueña C, Ballesteros-Ramírez R, Gomez-Cadena A, Barreto A, Prieto K, Quijano S, Aschner P, Martínez C, Zapata-Cardona MI, El-Ahanidi H, Jandus C, Florez-Alvarez L, Rugeles MT, Zapata-Builes W, Garcia AA, Fiorentino S.

Front Med (Lausanne). 2022 Sep 8;9:991873. doi: 10.3389/fmed.2022.991873. eCollection 2022.

PMID: 36160152 Free PMC article.

After JAK inhibitor failure: to cycle or to switch, that is the question - data from the JAK-pot collaboration of registries.

Pombo-Suarez M, Sanchez-Piedra C, Gómez-Reino J, Lauper K, Mongin D, Iannone F, Pavelka K, Nordström DC, Inanc N, Codreanu C, Hyrich KL, Choquette D, Strangfeld A, Leeb BF, Rotar Z, Rodrigues A, Kristianslund EK, Kvien TK, Elkayam O, Lukina G, Bergstra SA, Finckh A, Courvoisier DS.

Ann Rheum Dis. 2022 Sep 13:annrheumdis-2022-222835. doi: 10.1136/ard-2022-222835. Online ahead of print.

PMID: 36100351

Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema.

Ruwanpura SM, McLeod L, Dousha LF, Seow HJ, West AC, West AJ, Weng T, Alanazi M, MacDonald M, King PT, Bardin PG, Gabay C, Klinman DM, Bozinovski S, Vlahos R, Anderson GP, Rose-John S, Saad MI, Jenkins BJ.

Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2201494119. doi: 10.1073/pnas.2201494119. Epub 2022 Aug 29.

PMID: 36037355

Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation.

Brusini L, Dos Santos Pacheco N, Tromer EC, Soldati-Favre D, Brochet M.

J Cell Biol. 2022 Sep 5;221(9):e202111084. doi: 10.1083/jcb.202111084. Epub 2022 Aug 25.

PMID: 36006241

Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV.

Di Liberto G, Egervari K, Kreutzfeldt M, Schürch CM, Hewer E, Wagner I, Du Pasquier R, Merkler D.

Brain. 2022 Aug 27;145(8):2730-2741. doi: 10.1093/brain/awac102.

PMID: 35808999 Free PMC article.

Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update.

Aletaha D, Kerschbaumer A, Kastrati K, Dejaco C, Dougados M, McInnes IB, Sattar N, Stamm TA, Takeuchi T, Trauner M, van der Heijde D, Voshaar M, Winthrop KL, Ravelli A, Betteridge N, Burmester GR, Bijlsma JW, Bykerk V, Caporali R, Choy EH, Codreanu C, Combe B, Crow MK, de Wit M, Emery P, Fleischmann RM, Gabay C, Hetland ML, Hyrich KL, Iagnocco A, Isaacs JD, Kremer JM, Mariette X, Merkel PA, Mysler EF, Nash P, Nurmohamed MT, Pavelka K, Poor G, Rubbert-Roth A, Schulze-Koops H, Strangfeld A, Tanaka Y, Smolen JS.

Ann Rheum Dis. 2022 Aug 11:annrheumdis-2022-222784. doi: 10.1136/ard-2022-222784. Online ahead of print.

PMID: 35953263

G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis.

Rothammer N, Woo MS, Bauer S, Binkle-Ladisch L, Di Liberto G, Egervari K, Wagner I, Haferkamp U, Pless O, Merkler D, Engler JB, Friese MA.

Sci Adv. 2022 Aug 5;8(31):eabm5500. doi: 10.1126/sciadv.abm5500. Epub 2022 Aug 5.

PMID: 35930635 Free PMC article.

Intestinal CD8⁺ tissue-resident memory T cells: From generation to function.

Cheng L, Becattini S.

Eur J Immunol. 2022 Aug 19. doi: 10.1002/eji.202149759. Online ahead of print.

PMID: 35985020 Review.

Metacells untangle large and complex single-cell transcriptome networks.

Bilous M, Tran L, Cianciaruso C, Gabriel A, Michel H, Carmona SJ, Pittet MJ, Gfeller D.

BMC Bioinformatics. 2022 Aug 13;23(1):336. doi: 10.1186/s12859-022-04861-1.

PMID: 35963997 Free PMC article.

Neonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial.

Schmitz T, Doret-Dion M, Sentilhes L, Parant O, Claris O, Renesme L, Abbal J, Girault A, Torchin H, Houllier M, Le Saché N, Vivanti AJ, De Luca D, Winer N, Flamant C, Thuillier C, Boileau P, Blanc J, Brevaut V, Bouet PE, Gascoin G, Beucher G, Datin-Dorriere V, Bounan S, Bolot P, Poncelet C, Alberti C, Ursino M, Aupiais C, Baud O; BETADOSE trial study group; Groupe de Recherche en Obstétrique et Gynécologie.

Lancet. 2022 Aug 20;400(10352):592-604. doi: 10.1016/S0140-6736(22)01535-5.

PMID: 35988568 Clinical Trial.

Robust T-Cell Responses in Anti-CD20-Treated Patients Following COVID-19 Vaccination: A Prospective Cohort Study.

Madelon N, Lauper K, Breville G, Sabater Royo I, Goldstein R, Andrey DO, Grifoni A, Sette A, Kaiser L, Siegrist CA, Finckh A, Lalive PH, Didierlaurent AM, Eberhardt CS.

Clin Infect Dis. 2022 Aug 24;75(1):e1037-e1045. doi: 10.1093/cid/ciab954.

PMID: 34791081 Free PMC article.

Ceramide biosynthesis is critical for establishment of the intracellular niche of Toxoplasma gondii.

Nyonda MA, Kloehn J, Sosnowski P, Krishnan A, Lentini G, Maco B, Marq JB, Hannich JT, Hopfgartner G, Soldati-Favre D.

Cell Rep. 2022 Aug 16;40(7):111224. doi: 10.1016/j.celrep.2022.111224.

PMID: 35977499 Free PMC article.

N-acetylation of secreted proteins in Apicomplexa is widespread and is independent of the ER acetyl-CoA transporter AT1.

Nyonda MA, Boyer JB, Belmudes L, Krishnan A, Pino P, Couté Y, Brochet M, Meinnel T, Soldati-Favre D, Giglione C.

J Cell Sci. 2022 Aug 1;135(15):jcs259811. doi: 10.1242/jcs.259811. Epub 2022 Aug 5.

PMID: 35621049

Tissue-resident CD8 T cells in central nervous system inflammatory diseases: present at the crime scene and …guilty.

Merkler D, Vincenti I, Masson F, Liblau RS.

Curr Opin Immunol. 2022 Aug;77:102211. doi: 10.1016/j.coi.2022.102211. Epub 2022 May 26.

PMID: 35644112 Review.

Frequency of Abnormally Low Neuropsychological Scores in Post-COVID-19 Syndrome: the Geneva COVID-COG Cohort.

Voruz P, Jacot de Alcântara I, Nuber-Champier A, Cionca A, Allali G, Benzakour L, Lalive PH, Lövblad KO, Braillard O, Nehme M, Coen M, Serratrice J, Reny JL, Pugin J, Guessous I, Ptak R, Landis BN, Assal F, Péron JA.

Arch Clin Neuropsychol. 2022 Aug 9:acac068. doi: 10.1093/arclin/acac068. Online ahead of print.

PMID: 35942646 Free PMC article.

Adjuvanted recombinant zoster vaccine in solid organ transplant and hematopoietic stem-cell transplant recipients.

Provost-Olewczynska JX, Eberhardt CS.

Curr Opin Infect Dis. 2022 Aug 1;35(4):312-320. doi: 10.1097/QCO.0000000000000845. Epub 2022 Jul 5.

PMID: 35849521 Review.

Long-term persistence of antibodies after diphtheria/tetanus vaccination in immunosuppressed patients with inflammatory rheumatic diseases and healthy controls.

Mischlinger J, Jaeger VK, Ciurea A, Gabay C, Hasler P, Mueller RB, Siegrist CA, Villiger P, Walker UA, Hatz C, Bühler S.

Vaccine. 2022 Aug 5;40(33):4897-4904. doi: 10.1016/j.vaccine.2022.06.013. Epub 2022 Jul 7.

PMID: 35810064

TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells.

Kim J, Oh J, Peterson HM, Carlson JCT, Pittet MJ, Weissleder R.

Adv Biol (Weinh). 2022 Aug;6(8):e2200030. doi: 10.1002/adbi.202200030. Epub 2022 Jun 8.

PMID: 35675910

Pathogenesis-oriented therapy of psoriasis using biologics.

Boehncke WH, Brembilla NC.

Expert Opin Biol Ther. 2022 Jul 20:1-11. doi: 10.1080/14712598.2022.2100219. Online ahead of print.

PMID: 35815360

Motor-neuron-disease-like phenotype associated with IgLON5 disease.

Sista SR, Crum B, Aboseif A, Devine MF, Zekeridou A, Hammami MB, Rezk MM, Truffert A, Lalive PH, Kunchok A, McKeon A, Dubey D.

J Neurol. 2022 Jul 20. doi: 10.1007/s00415-022-11262-0. Online ahead of print.

PMID: 35857139

Comparison of tissue tropism and host response to enteric and respiratory enteroviruses.

Filipe IC, Tee HK, Prados J, Piuz I, Constant S, Huang S, Tapparel C.

PLoS Pathog. 2022 Jul 5;18(7):e1010632. doi: 10.1371/journal.ppat.1010632. eCollection 2022 Jul.

PMID: 35789345 Free PMC article.

Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis.

Cagol A, Schaedelin S, Barakovic M, Benkert P, Todea RA, Rahmanzadeh R, Galbusera R, Lu PJ, Weigel M, Melie-Garcia L, Ruberte E, Siebenborn N, Battaglini M, Radue EW, Yaldizli Ö, Oechtering J, Sinnecker T, Lorscheider J, Fischer-Barnicol B, Müller S, Achtnichts L, Vehoff J, Disanto G, Findling O, Chan A, Salmen A, Pot C, Bridel C, Zecca C, Derfuss T, Lieb JM, Remonda L, Wagner F, Vargas MI, Du Pasquier R, Lalive PH, Pravatà E, Weber J, Cattin PC, Gobbi C, Leppert D, Kappos L, Kuhle J, Granziera C.

JAMA Neurol. 2022 Jul 1;79(7):682-692. doi: 10.1001/jamaneurol.2022.1025.

PMID: 35575778 Free PMC article.

IL-38 orchestrates proliferation and differentiation in human keratinocytes.

Mermoud L, Shutova M, Diaz-Barreiro A, Talabot-Ayer D, Drukala J, Wolnicki M, Kaya G, Boehncke WH, Palmer G, Borowczyk J.

Exp Dermatol. 2022 Jul 14. doi: 10.1111/exd.14644. Online ahead of print.

PMID: 35833307

Genus-Specific Interactions of Bacterial Chromosome Segregation Machinery Are Critical for Their Function.

Pióro M, Matusiak I, Gawek A, Łebkowski T, Jaroszek P, Bergé M, Böhm K, Armitage J, Viollier PH, Bramkamp M, Jakimowicz D.

Front Microbiol. 2022 Jul 6;13:928139. doi: 10.3389/fmicb.2022.928139. eCollection 2022.

PMID: 35875543 Free PMC article.

Decreased Levels of SARS-CoV-2 Fusion-Inhibitory Antibodies in the Serum of Aged COVID-19 Patients.

Malézieux-Picard A, Abdul F, Herrmann FR, Caillon A, Ribaux P, Cambet Y, Yerly S, Baggio S, Vernaz N, Zekry D, Krause KH, Preynat-Seauve O, Prendki V.

Diagnostics (Basel). 2022 Jul 28;12(8):1813. doi: 10.3390/diagnostics12081813.

PMID: 36010162 Free PMC article.

Neutralization capacity of antibodies elicited through homologous or heterologous infection or vaccination against SARS-CoV-2 VOCs.

Bekliz M, Adea K, Vetter P, Eberhardt CS, Hosszu-Fellous K, Vu DL, Puhach O, Essaidi-Laziosi M, Waldvogel-Abramowski S, Stephan C, L'Huillier AG, Siegrist CA, Didierlaurent AM, Kaiser L, Meyer B, Eckerle I.

Nat Commun. 2022 Jul 4;13(1):3840. doi: 10.1038/s41467-022-31556-1.

PMID: 35787633 Free PMC article.

Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses.

Maarifi G, Martin MF, Zebboudj A, Boulay A, Nouaux P, Fernandez J, Lagisquet J, Garcin D, Gaudin R, Arhel NJ, Nisole S.

Cell Chem Biol. 2022 Jul 21;29(7):1113-1125.e6. doi: 10.1016/j.chembiol.2022.05.009. Epub 2022 Jun 20.

PMID: 35728599 Free PMC article.

Urine Output Monitoring for the Diagnosis of Early-Onset Acute Kidney Injury in Very Preterm Infants.

De Mul A, Parvex P, Héneau A, Biran V, Poncet A, Baud O, Saint-Faust M, Wilhelm-Bals A.

Clin J Am Soc Nephrol. 2022 Jul;17(7):949-956. doi: 10.2215/CJN.15231121. Epub 2022 Jun 28.

PMID: 35764392

A single respiratory tract infection early in life reroutes healthy microbiome development and affects adult metabolism in a preclinical animal model.

Yildiz S, Mazel-Sanchez B, Bonifacio JPP, Schmolke M.

NPJ Biofilms Microbiomes. 2022 Jul 2;8(1):51. doi: 10.1038/s41522-022-00315-x.

PMID: 35780244 Free PMC article.

Combining individual patient data from randomized and non-randomized studies to predict real-world effectiveness of interventions.

Seo M, Debray TP, Ruffieux Y, Gsteiger S, Bujkiewicz S, Finckh A, Egger M, Efthimiou O.

Stat Methods Med Res. 2022 Jul;31(7):1355-1373. doi: 10.1177/09622802221090759. Epub 2022 Apr 26.

PMID: 35469504 Free PMC article.

Alpha-1 Antitrypsin Reduces Disease Progression in a Mouse Model of Charcot-Marie-Tooth Type 1A: A Role for Decreased Inflammation and ADAM-17 Inhibition.

Zhukovsky N, Silvano M, Filloux T, Gonzalez S, Krause KH.

Int J Mol Sci. 2022 Jul 3;23(13):7405. doi: 10.3390/ijms23137405.

PMID: 35806409 Free PMC article.

The TAM-associated STIM1^I484R mutation increases ORAI1 channel function due to a reduced STIM1 inactivation break and an absence of microtubule trapping.

Kim JH, Carreras-Sureda A, Didier M, Henry C, Frieden M, Demaurex N.

Cell Calcium. 2022 Jul;105:102615. doi: 10.1016/j.ceca.2022.102615. Epub 2022 Jun 23.

PMID: 35792400

The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy.

Ho WW, Pittet MJ, Fukumura D, Jain RK.

Cancer Cell. 2022 Jul 11;40(7):701-702. doi: 10.1016/j.ccell.2022.05.016. Epub 2022 Jun 16.

PMID: 35714604 No abstract available.