Faculté de médecine Faculté de médecine

Simon Braun

Publications

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  • Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1. M Bagka, H Choi, M Héritier, H Schwaemmle, QTL Pasquer, SMG Braun, L Scapozza, Y Wu, S Hoogendoorn. Nature Communications (2023)
  • Neural stem cell metabolism: a critical role for mitochondria. C Scandella, F Petrelli, DL Moore, SMG Braun, M Knobloch. Trends in Endocrinology & Metabolism (2023)
  • BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex. SMG Braun, R Petrova, J Tang, A Krokhotin, EL Miller, Y Tang, G Panagiotakos, GR Crabtree. Genes & Development (2021)

  • mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution. CM Weber, A Hafner, JG Kirkland, SMG Braun, BZ Stanton, AN Boettiger, GR Crabtree. Nature Structural & Molecular Biology (2021).

  • High throughput screening identifies SOX2 as a super pioneer factor that inhibits DNA methylation maintenance at its binding sites. L Vanzan, H Soldati, V Ythier, S Anand, SMG Braun, N Francis, R Murr. Nature Communications (2021).

  • Lsh mediates gene repression through macroH2A deposition. K Ni, J Ren, X Xu ,Y He, R Finney, SMG Braun, N Hathaway, GR Crabtree, K Muegge. Nature Communications (2020)
  • Rapid and reversible epigenome editing by endogenous chromatin regulators. SMG Braun, JG Kirkland, EJ Chory, D Husmann, JP Calarco, GR Crabtree. Nature Communications (2017)
  • Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin. BZ Stanton, C Hodges, JP Calarco, SMG Braun, WL Ku, C Kadoch, K Zhao, GR Crabtree. Nature Genetics (2017)
  • Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. C Kadoch, RT Williams, JP Calarco, EL Miller, CM Weber, SMG Braun, JL Pulice, EJ Chory, GR Crabtree. Nature Genetics (2017)
  • Programming Hippocampal Neural Stem/Progenitor Cells into Oligodendrocytes Enhances Remyelination in the Adult Brain after Injury. SMG Braun, GA Pilz, RAC Machado, J Moss, B Becher, N Toni, S Jessberger. Cell Reports (2015)
  • Review. Adult neurogenesis: mechanisms and functional significance. SMG Braun and S Jessberger. Development (2014) 
  • SPOT14-positive neural stem/progenitor cells in the hippocampus respond dynamically to neurogenic regulators. M Knobloch, C Schoultz von, L Zurkirchen, SMG Braun, M Vidmar, S Jessberger. Stem Cell Reports (2014) 
  • Review: Adult neurogenesis and its role in neuropsychiatric disease, brain repair and normal brain function.  SMG Braun and S Jessberger. Neuropathology and Applied Neurobiology (2014) 
  • Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. *M Knobloch, *SMG Braun, L Zurkirchen, C Schoultz von, N Zamboni, MJ Araúzo-Bravo, WJ Kovacs, O Karalay, U Suter, RAC Machado, M Roccio, MP Lutolf, CF Semenkovich, S Jessberger. Nature (2013)
  • Temporal Control of Retroviral Transgene Expression in Newborn Cells in the Adult Brain. SMG Braun, RAC Machado, S Jessberger. Stem Cell Reports (2013) 
  • Review: Adult neurogenesis in the mammalian brain. SMG Braun and S Jessberger. Frontiers in Biology (2013)
  • Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells. M Wade, YC Li, AS Matani, SMG Braun, F Milanesi, LW Rodewald, GM Wahl. Oncogene (2012)
  • Preview. Crossing boundaries: direct programming of fibroblasts into neurons. SMG Braun and S Jessberger. Cell Stem Cell (2010)