patim

 

The Pathology Department conducts research into anatomical and clinical correlations in human pathology, and in the fields of cell biology, general immunology and immunopathology. 

Concerning cell biology, several teams study:

  • growth factors and the oncogenes involved in the differentiation and functioning of the lymphohematopoietic system
  • the functional role of certain parts of the cytoskeletal apparatus, in particular actin and intermediary filaments, and how they change in the course of the arterial pathology of scar-tissue formation and the development of epithelial tumours and conjunctive tissue
  • the structure and function of the cell membrane

Research in immunology focusses on:

  • Functional specialisation of T lymphocyte subsets under experimental and pathological conditions
  • Synthesis and function of cytokines secreted by cells of the immune system under experimental and pathological conditions
  • Regulation and function of antigen presentation under experimental and pathological conditions

Research in pathology focusses on:

  • Cellular interactions promoting the development of spontaneous and provoked autoimmunity
  • Role of antibodies and immune complexes in triggering vascular lesions
  • Role of immune responses in pathological manifestations associated with infectious disease
  • Intra- and inter-cellular communication leading to the development of cardiovascular disease

 

Honorary Professors

  • Dominique Belin - Honorary Professor
    The orphan genes of bacteriophage T4, a biological dark matter
  • Irène Garcia-Gabay
    Mediators involved in the regulation of responses to mycobacterial infections and inflammation
  • Beat Imhof - Honorary Professor
    Adhesion molecules and the process of cell migration

Research Groups

Department of Clinical Pathology, Hospital Department of Medical Genetics, of Laboratory and Pathology

Affiliated Clinical Groups

  • Constance Barazzone  (Department of Paediatrics)
    Factors influencing lung development: translational studies on animal and humans                                
  • Wolf-Henning Boehncke  (Department of Internal Medicine Specialities)
    Mechanisms of the pathologies of the cutaneous inflammation
  • Carlo Chizzolini (Department of Internal Medicine Specialities)
    Inflammation, autoimmunity and extracellular matrix
  • Cem Gabay (Department of Internal Medicine Specialities)
    Mechanisms of articular inflammation and joint damage in arthritis
  • Jorg Seebach (Department of Internal Medicine Specialities)
    Laboratory for Transplantation Immunology
  • Claire-Anne Siegrist (Department of Pediatry)
    Center of Vaccinology and Neonatal Immunology
  • Patrice Lalive d'Epinay (Department of Clinical Neurosciences)
    Neuroimmunology, Experimental autoimmune encephalitis, Multiple sclerosis.
  • Monique Ghannage (Department of Internal Medicine Specialities)
    Contribution of macroautophagy to the immune response during autoimmune diseases
  • Jean Villard and Sylvie Ferrari-Lacraz (Department of Internal Medicine Specialities)
    Transplantations and Osteoimmonology
  • Pascal Senn (Department of Clinical Neurosciences)
    Division of ENT and Head-and-Neck Surgery