A review of the journey of an old drug
Among different strategies to develop novel therapies, identifying new uses of an already approved or investigational drug is an effective and cost effective strategy. Clofazimine, a drug initially developed as an anti-tuberculosis treatment was repurposed many times since its first discovery in the 1950s.
Clofazimine, initially developed as an anti-tuberculosis treatment, has been repurposed for leprosy, non-tuberculous myobacterial infections (NTM), cancer, inflammation and multidrug-resistant tuberculosis (MDR TB). © Graphical Abstract from Xu et al. 2023
To discover the interesting journey of clofazimine and how it illustrates drug repurposing in modern pharmacology, download their recent review published in Biomedicine and Pharmacotherapy.