School of Chemistry and Biochemistry School of Chemistry and Biochemistry

Thierry Soldati

Publications

You can have a look at my ORCID page,

and visit our Archive Ouverte for an access to most of the PDF version of our publications

2024

2023

 

          • Burdet F., Allard P.M., Nothias L.F., Kirchhoffer O., Gaudry A., Moretti S., Engler R., Quiros-Guerrero L.M., Ferreira-Queiroz E., Nitschke J., Hanna N., Wu C., Grondin A., David B., Soldati T., Wolfrum C., Carreira E., Wolfender J.L., Pagni M. and Mehl F. (2023) Application of the RDF framework to integrate heterogenous experimental data of a large chemo- and biodiverse collection from a research collaborative project. chemRxiv https://doi.org/10.26434/chemrxiv-2023-4hlgd
          • Kirchhoffer O.A., Nitschke J., Allard P.M, Marcourt L., David B., Grondin A., Hanna N., Queiroz A.F., Soldati T. and Wolfender J.L. (2023) Targeted isolation of natural analogs of anti-mycobacterial hit compounds based on the metabolite profiling of a large collection of plant extracts. Frontiers in Natural Products  https://doi.org/10.3389/fntpr.2023.1279761
          • Vines J.H., Maib H., Buckley C., Gueho A., Zhu Z., Soldati T., Murray D.H. and King J.S. (2023) A PI(3,5)P2 reporter reveals PIKfyve activity and dynamics on  macropinosomes and phagosomes. Journal of Cell Biology  https://doi.org/10.1083/jcb.202209077
          • Raykov L., Mottet M., Nitschke J. and Soldati T. (2023) A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum. eLife  https://doi.org/10.7554/eLife.85727
          • Lefrançois L.H., Nitschke J., Panis G., Prados J., Butler R.E., Mendum T.A., Hanna N., Stewart G.R. and Soldati T. (2023) Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals genetic requirement for virulence and survival in amoebae and microglial cells. bioRxiv 2023.03.22.533734 https://doi.org/10.1101/2023.03.22.533734

2022

2021

          • Bosmani C, Perret A, Leuba F, Guého A, Hanna N, Soldati T. (2021) Disruption of vacuolin microdomains in the host Dictyostelium discoideum increases resistance to Mycobacterium marinum-induced membrane damage and infection. Preprint: bioRxiv 468763; https://doi.org/10.1101/2021.11.16.468763
          • Mottet M, Bosmani C, Hanna N, Nitschke J, Lefrancois LH, Soldati T. (2021) Novel Single-Cell and High-Throughput Microscopy Techniques to Monitor Dictyostelium discoideum-Mycobacterium marinum Infection Dynamics. Methods Mol Bio doi: 10.1007/978-1-0716-1460-0_7
          • Raykov L, Mottet M, Nitschke J, Soldati T. (2021) The Dictyostelium discoideum E3 ubiquitin ligase TrafE coordinates endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum. Preprint: bioRxiv 450281; https://doi.org/10.1101/2021.06.29.450281
          • Klionsky, D.J., … Soldati, T., et al (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy doi:10.1080/15548627.2020.1797280
          • Hanna N, Koliwer-Brandl H, Lefrançois L, Kalinina V, Cardenal-Muñoz E, Appiah J, Leuba F, Guého A, Hilbi H, Soldati T, Barisch C. (2021) Zn2+ Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn2+ Exporter CtpC. mBio. doi:10.1128/mBio.01313-20

2020

          • Parhizkar M, Di Marzo Serugendo G, Nitschke J, Hellequin L, Wade A, and Soldati T. (2020) Second-order agent-based models of emergent behaviour of Dictyostelium discoideum and their inspiration for swarm robotics. Artificial Life and Robotics doi:10.1007/s10015-020-00656-w
          • Parhizkar M, Di Marzo Serugendo G, Nitschke J, Hellequin L, Wade A, and Soldati T. (2020) First-order agent-based models of emergent behaviour of Dictyostelium discoideum and their inspiration for swarm robotics. Artificial Life and Robotics doi:10.1007/s10015-020-00657-9
          • Buckley CM, Pots H, Guého A, Vines JH, Munn CJ, Phillips BA, Gilsbach B, Traynor D, Nikolaev A, Soldati T, Parnell AJ, Kortholt A, and King JS. (2020) Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria. Current Biology doi: 10.1016/j.cub.2020.05.049
          • Bosmani C, Leuba F, Hanna N, Bach F, Burdet F, Pagni M, Hagedorn M, Soldati T.(2020) Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideum. J. Cell. Sci. doi: 10.1242/jcs.242974
          • Ferling I, Dunn JD, Ferling A, Soldati T, Hillmann F. (2020) Conidial Melanin of the Human-Pathogenic Fungus Aspergillus fumigatus Disrupts Cell Autonomous Defenses in Amoebae. mBio. doi: 10.1128/mBio.00862-20.
          • Leuba F, Soldati T. (2020) The RB008 antibody does not recognize D. discoideum NoxA by western blot. Antib. Rep. doi:10.24450/journal/abrep.2020.e190
          • Mottet M, Soldati T. (2020) AI842, AI843, AI844 and AI177 antibodies do not recognize a FLAG-tagged protein by immunofluorescence in D. discoideum cells. Antib. Rep. doi: 10.24450/journals/abrep.2020.e126
          • Lamrabet O, Melotti A, Burdet F, Hanna N, Perrin J, Nitschke J, Pagni M, Hilbi H, Soldati T, Cosson P. (2020) Transcriptional Responses of Dictyostelium discoideum Exposed to Different Classes of Bacteria. Front. Microbiol. doi: 10.3389/fmicb.2020.00410
          • Hanna N, Kicka S, Chiriano G, Harrison C, Ouertatani Sakouhi H, Trofimov V, Kranjc A, Nitschke J, Pagni M, Cosson P, Hilbi H, Scapozza L, Soldati T. (2020) Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models. Front. Microbiol. doi: 10.3389/fmicb.2020.00266
          • Knobloch P, Koliwer-Brandl H, Arnold FM, Hanna N, Gonda I, Adenau S, Personnic N, Barisch C, Seeger MA, Soldati T, Hilbi H. (2020) Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes. Cell Microbiol. doi: 10.1111/cmi.13163
          • Leuba F, Soldati T. (2020) AI842, AI843, AI844 and AI177 antibodies do not recognize a FLAG-tagged protein expressed in D. discoideum by western blot. Antib. Rep. doi: 10.24450/journals/abrep.2020.e111
          • Butler RE, Smith AA, Mendum TA, Chandran A, Wu H, Lefrançois L, Chambers M, Soldati T, Stewart GR. (2020) Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum. The ISME Journal. doi: 10.1038/s41396-019-0572-z

2019

          • Leuba F, Soldati T. (2019) RB155, RB156 and RB189 antibodies do not recognize the D. discoideum Tsg101 protein by western blot. Antib. Rep. doi: 10.24450/journals/abrep.2019.e109.
          • Buckley CM, Pots H, Guého A, Phillips BA, Gilsbach B, Traynor D, Nikolaev A, Soldati T, Parnell AJ, Kortholt A, King JS. Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria. Preprint: bioRxiv 763748; https://doi.org/10.1101/763748
          • Soldati T. (2019) Cellular Microbiology 1999-2019. Cell Microbiol. doi: 10.1111/cmi.13106
          • Ferling I, Dunn JD, Ferling A, Soldati T, Hillmann F. Conidial melanin of the human pathogenic fungus Aspergillus fumigatus disrupts cell autonomous defenses in amoebae. Preprint: bioRxiv 730879; https://doi.org/10.1101/730879
          • Soldati T, Cardenal-Muñoz E. (2019) A brief historical and evolutionary perspective on the origin of cellular microbiology research. Cell Microbiol. doi: 10.1111/cmi.13083
          • Luscher A, Fröhlich F, Barisch C, Littlewood C, Metcalfe J, Leuba F, Palma A, Pirruccello M, Cesareni G,Stagi M, Walther TC, Soldati T, De Camilli P, Swan LE. (2019) Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum. Mol. Biol. Cell. https://doi.org/10.1091/mbc.E18-08-0510
          • Luscher A, Fröhlich F, Barisch B, Littlewood C, Metcalfe J, Leuba F, Palma A, Pirruccello M, Cesareni G,Stagi M, Walther TC, Soldati T, De Camilli P, Swan LE. Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum. Preprint: bioRxiv 616664; https://doi.org/10.1101/616664
          • Diop EA, Queiroz EF, Marcourt L, Kicka S, Rudaz S, Diop T, Soldati T, Wolfender JL. (2019) Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolites. J Ethnopharmacol. doi: 10.1016/j.jep.2019.111832
          • Guého A, Bosmani C, Soldati T. Proteomic characterization of the Mycobacterium marinum-containing vacuole in Dictyostelium discoideum. Preprint: bioRxiv 592717; https://doi.org/10.1101/592717
          • Hanna N, Burdet F, Melotti A, Bosmani C, Kicka S, Hilbi H, Cosson P, Pagni M, Soldati T. Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress. Preprint: bioRxiv 590810; https://doi.org/10.1101/590810
          • López-Jiménez AT, Hagedorn M, Delince MJ, McKinney J, Soldati T. The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell autonomous level and collaborative exclusion. Preprint: bioRxiv 586263; https://doi.org/10.1101/586263
          • Bosmani C, Bach Frauke, Leuba F, Hanna N, Burdet F, Pagni M, Hagedorn M, Soldati T. Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis. Preprint: bioRxiv 582049; https://doi.org/10.1101/582049
          • Lefrançois LH, Kalinina V, Cardenal-Muñoz E, Hanna N, Koliwer-Brandl H, Appiah J, Leuba F, Hilbi H, Soldati T, Barisch C. (2019) Zn2+ intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC. Preprint: bioRxiv 575217; https://doi.org/10.1101/575217
          • Thewes S, Soldati T, Eichinger L. (2019) Editorial: Amoebae as host models to study the interaction with pathogens. Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2019.00047
          • Buckley CM, Heath VL, Guého A, Bosmani C, Knobloch P, Sikakana P, Personnic N, Dove SK, Michell RH, Meier R, Hilbi H, Soldati T, Insall RH, King JS. (2019) PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection. PLoS Pathog. doi: 10.1371/journal.ppat.1007551
          • Koliwer-Brandl H, Knobloch P, Barisch C, Welin A, Hanna N, Soldati T, Hilbi H. (2019) Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation and escape to the cytosol. Cell Microbiol. doi: 10.1111/cmi.13008

2018

          • López-Jiménez AT, Cardenal-Muñoz E, Leuba F, Gerstenmaier L, Barisch C, Hagedorn M, King JS, Soldati T. (2018) The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection. PLoS Pathog. doi: 10.1371/journal.ppat.1007501
          • Kicka S, Hanna N, Chiriano G, Harrison C, Ouertatani Sakouhi H, Trofimov V, Kranjc A, Hilbi H, Cosson P, Scapozza L, Soldati T (2018).  Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models. Preprint: bioRxiv 497032; https://doi.org/10.1101/497032
          • Barisch C, Kalinina V, Lefrançois LH, Appiah J, López-Jiménez AT, Soldati T. (2018) Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and B knockout on bacteria killing.  J. Cell. Sci. doi: 10.1242/jcs.222000
          • Sattler N, Bosmani C, Barisch C, Guého A, Gopaldass N, Marco Dias, Leuba F, Bruckert F, Cosson P, Soldati T. (2018) Functions of the Dictyostelium LIMP-2/CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defence. J. Cell. Sci. doi: 10.1242/jcs.218040
          • Barisch C, Kalinina V, Lefrançois LH, Appiah J, Soldati T. (2018) Think zinc: Role of zinc poisoning in the intraphagosomal killing of bacteria by the amoeba Dictyostelium. Preprint: bioRxiv 356949; https://doi.org/10.1101/356949
          • López-Jiménez AT, Cardenal-Muñoz E, Leuba F, Gerstenmaier L, Hagedorn M, King JS, Soldati T. (2018) ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole. Preprint: bioRxiv 334755; https://doi.org/10.1101/334755
          • Dhakshinamoorthy R, Bitzhenner M, Cosson P, Soldati T, Leippe M. (2018) The saposin-like protein AplD displays pore-forming activity and participates in defense against bacterial infection during a multicellular stage of Dictyostelium discoideum. Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2018.00073
          • Diop EA, Queiroz EF, Kicka S, Rudaz S, Diop T, Soldati T, Wolfender JL. (2018) Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity. J Ethnopharmacol. doi: 10.1016/j.jep.2017.12.037
          • Trofimov V, Kicka S, Mucaria S, Hanna N, Ramon-Olayo F, Vela-Gonzalez Del Peral L, Lelièvre J, Ballell L, Scapozza L, Besra GS, Cox JAG, Soldati T. (2018) Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets. Sci. Rep. doi: 10.1038/s41598-018-22228-6
          • Nicolussi A, Dunn JD, Mlynek G, Bellei M, Zamocky M, Battistuzzi G, Djinović-Carugo K, Furtmüller PG, Soldati T, Obinger C. (2018) Secreted Heme Peroxidase from Dictyostelium discoideum: Insights into Catalysis, Structure and Biological Role. JBC. doi: 10.1074/jbc.RA117.000463
          • Cardenal-Muñoz E, Barisch C, Lefrançois LH, López-Jiménez AT, Soldati T. (2018) When Dicty Met Myco, a (Not So) Romantic Story about One Amoeba and Its Intracellular Pathogen. Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2017.00529
          • Dunn JD, Bosmani C, Barisch C, Raykov L, Lefrançois LH, Cardenal-Muñoz E, López-Jiménez AT, Soldati T. (2018) Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses. Front. Immunol. doi: 10.3389/fimmu.2017.01906

2017

          • Ouertatani-Sakouhi H, Kicka S, Chiriano G, Harrison CF, Hilbi H, Scapozza L, Soldati T, Cosson P. (2017) Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model. PLoS One. 12(7):e0181121
          • Domínguez-Martín E, Cardenal-Muñoz E, King JS, Soldati T, Coria R, Escalante R. (2017) Methods to Monitor and Quantify Autophagy in the Social Amoeba Dictyostelium discoideum. Cells. 6(3). pii: E18
          • Barisch C, Soldati T. (2017) Breaking fat! How mycobacteria and other intracellular pathogens manipulate host lipid droplets. Biochimie. pii: S0300-9084(17)30145-1
          • Egea J, ... Dunn, JD et al ... Soldati T, ... and Daiber A. (2017) European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biol. 13:94-162.
          • Cardenal-Muñoz E, Arafah S, López-Jiménez AT, Kicka S, Falaise A, Bach F, Schaad O, King JS, Hagedorn M, Soldati T. (2017) Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner. PLoS Pathog. 13(4):e1006344.
          • Barisch C, Soldati T. (2017) Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions. PLoS Pathog. 13(1):e1006095.
          • Leiba J, Sabra A, Bodinier R, Marchetti A, Lima WC, Melotti A, Perrin J, Burdet F, Pagni M, Soldati T, Lelong E, Cosson P. (2017) Vps13F links bacterial recognition and intracellular killing in Dictyostelium. Cell Microbiol. doi: 10.1111/cmi.12722
          • Mesquita, A., Cardenal-Muñoz, E., Dominguez, E., Muñoz-Braceras, S., Nuñez-Corcuera, B., Philips, B.A., Tábara, L.C., Xiong, Q., Coria, R., Eichinger, L., Golstein, P., King, J.S., Soldati, T., Vincent, O. and Escalante, R. (2017) Autophagy in Dictyostelium: mechanisms, regulation and disease in a simple biomedical model Autophagy. 13(1):24-40

2016

          • Buckley, C., Gopaldass, N., Johnston, S.A., Soldati, T., Insall, R.H, and King, J.S. (2016) WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors. Proc Natl Acad Sci USA 113(40): E5906-E5915
          • Zhang, X., and Soldati, T (2016) Of amoebae and men: Extracellular DNA traps as an ancient cell-intrinsic defence mechanism Frontiers in Immunology 7:269
          • Van Voorhis, W.C., Adams, J.H., ..., Kicka, S., ..., Trofimov, V., … Soldati, T., et al. (2016) Open-source drug discovery with the Malaria Box compound collection for neglected diseases and beyond. PLoS Pathogens 12(7):e1005763
          • Delincé, M., Bureau, J.-B., López Jiménez, A.T., Cosson, P., Soldati, T., and McKinney J. (2016) A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions. Lab on a Chip 16(17):3276-85
          • Guého, A., Bosmani, C., Molle, V., Gopaldass, N., Soldati, T., and Letourneur, F. (2016) Dictyostelium EHD associates with Dynamin and participate in phagosome maturation. J. Cell Sci 129(12):2354-6
          • Zhang, X., Zhuchenko, O., Kuspa, A., and Soldati, T. (2016) Social amoebae trap and kill bacteria by casting DNA nets. Nat. Commun. 7:10938
          • Slepikas, L., Chiriano, G., Perozzo, R., Tardy, S., Kranjc-Pietrucci, A., Patthey-Vuadens, O., Ouertatani-Sakouhi, H., Kicka, S., Harrison, C., Scrignari, T., Perron, K., Hilbi, H., Soldati, T., Cosson, P., Tarasevicius, E., Scapozza, L. (2016) In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA J. Med. Chem Jan 5

2015

          • Dunn J.D., Alvarez L.A., Zhang X., Soldati T. (2015) Reactive oxygen species and mitochondria: A nexus of cellular homeostasis. Redox Biol. 6:472-85
          • Xie X., Gutiérrez A., Trofimov V., Szilagyi I., Soldati T., Bakker E. (2015) Charged Solvatochromic Dyes as Signal Transducers in pH Independent Fluorescent and Colorimetric Ion Selective Nanosensors. Anal Chem. 87(19):9954-9
          • Harrison, C.F., Chiriano, G., Hoffmann, C., Petermann, O., Kranjc-Pietrucci, A., Patthey Vuadens, O., Kicka, S., Trovimov, V., Ouertatani-Sakouhi, H., Cosson, P., Soldati, T., Scapozza, L., and Hilbi, H. (2015) Amoebae-based screening reveals a novel family of compounds restricting intracellular Legionella. ACS Infectious Diseases 1 (7), pp 327–338
          • Harrison C.F., Kicka, S., Kranjc-Pietrucci, A., Finsel, I., Chiriano, G., Ouertatani-Sakouhi, H., Soldati, T., Scapozza, L., and Hilbi, H. (2015) Adrenergic antagonists restrict replication of Legionella. Microbiology 161(7):1392-406
          • Barisch, C., López-Jiménez, A.T., and Soldati, T. (2015) Live Imaging of Mycobacterium marinum Infection in Dictyostelium discoideum. Methods Mol Biol 1285:369-85.
          • Xie, X., Gutiérrez, A., Trofimov, T., Szilagyi, I., Soldati, T., and Bakker E. (2015) Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive Dyes. Chimia 69, No. 4 1-3
          • Barisch, C., Paschke, P., Hagedorn, M., Maniak, M., and Soldati, T. (2015) Lipid Droplet Dynamics at Early Stages of Mycobacterium marinum Infection in Dictyostelium. Cell Microbiol. 17(9):1332-1349
          • Gerstenmaier, L., Pilla, R., Herrmann, L., Herrmann, H., Prado, M., Villafano, G.J., Kolonko, M., Reimer, R., Soldati, T., King, J.S., Hagedorn, M. (2015) The Autophagic Machinery Ensures non-lytic Transmission of Mycobacteria. Proc Natl Acad Sci USA 17;112(7):E687-92

2014

          • Kicka, S., Trofimov, V., Harrison, C.F., Ouertatani-Sakouhi, H., McKinney, J., Scapozza, L., Hilbi, H., Cosson, P., and Soldati, T. (2014) Establishment and validation of cell-based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii – Mycobacterium marinum host-pathogen system. PLoS ONE 9(1):e87834

2013

          • Zhang, X., and Soldati, T. (2013) Detecting, visualizing and quantitating the generation of reactive oxygen species in an amoeba model system. J. Vis. Exp. (81), e50717
          • Harrison, C.F., Kicka, S., Trofimov, V., Berschl, K., Ouertatani-Sakouhi, H., Ackermann, N., Hedberg, C., Cosson, P., Soldati, T., Hilbi, H. (2013) Exploring anti-bacterial compounds against intracellular Legionella. PLoS ONE 13;8(9):e74813
          • King, J.S., Guého, A., Hagedorn, M., Gopaldass, N., Leuba, F., Soldati, T., and Insall, R.H. (2013) WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion. Mol Biol Cell 24(17):2714-26
          • Zhang, X., Krause, K.H. Xenarios, I., Soldati, T., and Boeckmann B. (2013) Evolution of the Ferric Reductase Domain (FRD) Superfamily: Modularity, Functional Diversification, and Signature Motifs. PLoS ONE 8(3):e58126.
          • Sattler, N., Monroy, R., and Soldati, T. (2013) Quantitative analysis of phagocytosis in Dictyostelium. Methods Mol. Biol. 983:383-402.
          • Arafah, S., Kicka, S., Trofimov, T., Hagedorn, M., Andreu, N., Wiles, S, Robertson, B. and Soldati, T. (2013) Setting Up and Monitoring an Infection of Dictyostelium discoideum with Mycobacteria. Methods Mol. Biol. 83:403-1.

2012

          • Soldati. T., and Neyrolles, O. (2012) Mycobacteria and the Intraphagosomal Environment: Take It With a Pinch of Salt(s)! Traffic 13(8):1042-52.
          • Dieckmann, R., Monroy, R., Bloomfield, G., Ruppert, T., and Soldati, T. (2012) A balance in the delivery of ER components and the vacuolar proton pump to the phagosome depends on Myosin IK in Dictyostelium. Mol. Cell Proteomics 11(10):886-900.
          • Friedrich, N., Hagedorn, M., Soldati, T., and Soldati-Favre, D. (2012) Prison break: Pathogen strategies for host cell egress. Microbiology and Molecular Biology Reviews 76(4):707-20.
          • Klionsky, D.J., … Soldati, T., et al (2012) Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy in Higher Eukaryotes Autophagy 8:4, 1–100
          • Essid, M., Gopaldass, N., Yoshida, K., Merrifield, C.,and Soldati, T. Rab8a regulates the exocyst-mediated kiss-and-run discharge of the Dictyostelium contractile vacuole. (2012) Mol. Biol. Cell 23(7):1267-82.
          • Lima, W.C., Leuba, F., Soldati , T., and Cosson, P. (2012) Mucolipin controls lysosome exocytosis in Dictyostelium. J Cell Sci. 125(Pt 9):2315-22.
          • Tollis, S., Gopaldass, N., Soldati, T., Endres R.G. (2012) How one cell eats another: principles of phagocytosis. Chapter6: in Systems Microbiology: Current Topics and Applications. Ed B.D. Robertson and B.W. Wren. Caister Academic Press.
          • Jaiswal, P., Soldati, T., Thewes, S., and Baskar, R. (2012) Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds BMC Dev Biol. 12(1):5.
          • Gopaldass, N., Patel, D., Kratzke, R., Dieckmann, R., Hausherr, S., Hagedorn, M., Neuhaus, E.M., Hoffman, E., Hille, K., Kuznetsov, S., and Soldati, T. (2012) Dynamin A, Myosin IB and Abp1 couple phagosome maturation to F-actin binding. Traffic 13(1):120-30.

2011

          • Carnell, M., Zech, T., Calaminus, S., Ura, S., Hagedorn, M., Johnston, S., May, R., Soldati, T., Machesky L., and Insall R. (2011) Actin Polymerization Driven by WASH Causes V-ATPase Retrieval and Vesicle Neutralization Before Exocytosis. J. Cell Biol 193(5):831-9.
          • Lelong, E., Marchetti, A., Guého, A., Lima, W., Sattler, N., Molmeret, M., Hagedorn, M., Soldati, T., and Cosson, P. (2011) Role of magnesium and a phagosomal P-type ATPase in intracellular bacterial killing. Cell. Microbiol. 13(2):246-58

2010

          • Boulais, J., Trost, M., Landry, C., Dieckmann, R., Levy, E., Soldati, T., Michnick, S., Thibault, P., and Desjardins. M. (2010) Molecular characterization of the evolution of phagosomes. Mol. Syst. Biol. 6:423
          • Calvo-Garrido, J., Carilla-Latorre, S., Kubohara, Y., Santos, N., Mesquita, A., Soldati, T., Golstein, P., and Escalante, R. (2010) Autophagy in Dictyostelium: genes and pathways, cell death and infection. Autophagy. 6:688-701
          • Pino, P., Aeby, E., Foth, B.J., Sheiner, L., Soldati, T., Schneider, A., and Soldati-Favre, D. (2010) Mitochondrial translation in absence of local tRNA aminoacylation and methionyl-tRNAMet formylation in Apicomplexa. Mol. Microbiol. 76(3):706-718.
          • Dieckmann, R., von Heyden, SY, Kistler, C., Gopaldass, N., Hausherr, S., Crawley, S.W., Schwarz, E, Diensthuber, R.F., Côté, G.P., Tsiavaliaris, G., and Soldati, T. (2010) A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiency. Mol. Biol. Cell 21(9):1505-1518.

2009

          • Hagedorn, M., Kyle H. Rohde, David G. Russell, and Soldati, T. (2009) Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts. Science 323, 1729-1733.
          • Dieckmann, R., and Soldati, T. (2009) Phagosome proteomes unite! A virtual model of maturation as a tool to study pathogen-induced changes. In Intracellular Niches of Microbes: A Pathogens Guide Through the Host Cell, Ed Schaible, U.E., and Haas, A. John Wiley & Sons, Ltd, 107-124.
          • Hagedorn, M., and Soldati, T. (2009) Mycobacterium marinum. In Intracellular Niches of Microbes: A Pathogens Guide Through the Host Cell, Ed Schaible, U.E., and Haas, A. John Wiley & Sons, Ltd, 455-467.

2008

2007

          • Pino, P., Foth, B.J., Kwok, L., Sheiner, L., Schepers, R., Soldati, T., and Soldati, D. (2007) Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii. PLOS Pathogens. 3(8):e115.
          • Hagedorn, M., and Soldati, T. (2007) Flotillin and the RacH GTPase modulate intracellular immunity of Dictyostelium to Mycobacterium marinum infection. Cell Microbiol. 9, 2716-2733.

2006

          • Gotthardt, D., Blancheteau, V., Bosserhoff, A., Ruppert, T., Delorenzi, M., and Soldati, T. (2006) Proteomic fingerprinting of phagosome maturation reveals a role for a Galpha during uptake. Mol. Cell. Proteomics. 5, 2228-2243.
          • Yoshida, K., and Soldati, T. (2006) Dissection of amoeboid movement into two mechanically distinct modes. J. Cell Sci. 119, 3833-3844
          • Hagedorn, M., Neuhaus, E.N., Soldati, T. (2006) Optimised fixation and immunofluorescence protocols for Dictyostelium cells. Methods Mol. Biol. 346, 327-338.
          • Gotthardt, D., Dieckmann, R., Blancheteau, V., Kistler, C., Reichardt, F., and Soldati, T. (2006) Preparation of intact, highly purified phagosomes from Dictyostelium. Methods Mol. Biol., 346, 439-448.
          • Soldati, T., and Schliwa, M. (2006) Powering membrane traffic in endocytosis and recycling. Nat. Rev. Mol. Cell Biol. 7, 897-908.

2004

          • Lefkir, Y., Malbouyres, M., Gotthardt, Ozinsky, A., D., Bruckert, F., Aderem, A.A., Soldati, T., Cosson, P., and Letourneur, F. (2004) Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis. Mol. Biol. Cell, 15, 861-869.
          • Soldati, T. and Kistler, C. (2004) Do class I myosins exert their function through regulation of actin dynamics? Cell Motility. From Molecules to Organisms, Ed Ridley, A., Peckham, M. and Clark, P. John Wiley & Sons, Ltd, 40-59.

2003

          • Soldati, T. (2003) Unconventional myosins, actin dynamics and endocytosis: A ménage à trois? Traffic, 4, 358-366.

2002

          • Gotthardt, D., Warnatz, H.J., Henschel, O., Brückert, F., Schleicher, M., and Soldati, T. (2002) High resolution dissection of phagosome maturation reveals distinct membrane trafficking phases. Mol. Biol. Cell 13, 3508-3520.
          • Herm-Götz, A., Weiss, S., Stratmann, R., Fujita-Becker, S., Ruff, C., Meyhöfer, E., Soldati, T, Manstein, D.J., Geeves, M.A., and Soldati, D. (2002) Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end directed motor. EMBO J. 21, 2149-2158.
          • Neuhaus, E.M., Almers, W., and Soldati, T. (2002) Morphology and dynamics of the endocytic pathway in Dictyostelium discoideum. Mol. Biol. Cell 13, 1390-1407.

2001

          • Delbac, F., Sänger A., Neuhaus, E.M., Stratmann, R., Ajioka, J.W., Toursel, C., Herm-Götz, A., Tomavo S., Soldati, T., and Soldati, D. (2001) Toxoplasma gondii myosins B/C: One gene, two tails, two localizations and a role in parasite division. J. Cell Biol., 155, 613-623.
          • Gillespie, P.G., Soldati, T., et al. (2001) Myosin-I nomenclature. J. Cell Biol. 155, 704-704.

2000

          • Monnat, J., Neuhaus, E.M., Pop, M.S., Ferrari, D., Kramer, B., and Soldati, T. (2000) Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomerase. Mol. Biol. Cell 11, 3469-3484.
          • Neuhaus, E.M., and Soldati, T. (2000) A myosin I is involved in membrane recycling from early endosomes. J. Cell Biol. 150, 1013-1026.
          • Lang, T., Wacker, I., Wunderlich, I., Rohrbach, A., Giese, G., Soldati, T., and Almers, W. (2000) Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells. Biophys. J., 78, 2863-2877.
          • Hettmann, C., Herm, A., Geiter, A., Frank, B., Schwarz, E., Soldati, T., and Soldati, D. (2000) A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization. Mol. Biol. Cell 11, 1385-1400.
          • Geissler, H., Ullmann, R., and Soldati, T. (2000) The tail domain of myosin M catalyses nucleotide exchange on Rac1-GTPases and can induce actin-driven surface protrusions. Traffic 1, 399-410.
          • Schwarz, E.C., Neuhaus, E.M., Kistler, C., Henkel, A.W., and Soldati, T. (2000) Dictyostelium myosin IK is involved in the maintenance of cortical tension and affects motility and phagocytosis. J. Cell Sci., 113, 621-633.

Before 2000

          • Schwarz, E.C., Geissler, H., and Soldati, T. (1999) A potentially exhaustive screening strategy reveals two novel divergent myosins in Dictyostelium. Cell Biochem. Biophys. 30, 413-435.
          • Ulbricht, B., and Soldati, T. (1999) Production of reagents and optimization of methods for studying calmodulin-binding proteins. Prot. Expr. Purif. 15, 24-33.
          • Neuhaus, E.M., and Soldati, T. (1999) Molecular mechanisms of membrane trafficking - What do we learn from Dictyostelium discoideum ? Protist 150, 235-243.
          • Soldati, T., Schwarz, E., and Geissler, H. (1999) Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodeling. Protoplasma 209, 28-37.
          • Soldati, T., Geissler, H., and Schwarz, E. (1999) How many is enough ? Exploring the myosin repertoire in the model eukaryote Dictyostelium discoideum. Cell Biochem. Biophys. 30, 389-411.
          • Neuhaus, E., Horstmann, H., Almers, W., Maniak, M., and Soldati, T. (1998) Ethane-freezing/methanol-fixation of cell monolayers. A procedure for improved preservation of structure and antigenicity for light and electron microscopies. J. Struct. Biol. 121, 326-342.
          • Monnat, J., Hacker, U., Geissler, H., Rauchenberger, R., Neuhaus, E., Maniak, M., and Soldati, T. (1997) Dictyostelium discoideum Protein Disulfide Isomerase, an endoplasmic reticulum resident enzyme lacking a KDEL-type retrieval signal. FEBS Lett., 418, 357-362.
          • Lang, T., Wacker, I., Steyer, J., Kaether, C., Wunderlich, I., Soldati, T., Gerdes, H. and Almers, W. (1997) Ca2+ -triggered peptide secretion in single cells imaged with green fluorescent protein and evanescent-wave microscopy. Neuron 18, 857-863.
          • Komiyama, M., Soldati, T., von Arx, P. and Perriard, J.-C. (1996) The sorting specificity of myosin alkali light chain isoproteins reflects the sequence of developmental expression as determined by double epitope-tagging competition. J. Cell Sci. 109, 2089-2099.
          • Von Arx, P., Bantle, S., Soldati, T. and Perriard, J.-C. (1995) Dominant Negative Effect of Cytoplasmic Actin Isoproteins on Cardiomyocyte Cytoarchitecture and Function. J. Cell Biol. 131(6), 1759-1773.
          • Riederer, M.A., Soldati, T., Dirac-Svejstrup, A.B., and Pfeffer, S.R. (1995) Expression of Rab9 protein in Escherichia coli, Purification and isoprenylation in vitro. Meth. Enzym. 257, 15-21.
          • Soldati, T., Rancaño, C., Geissler, H. and Pfeffer, S.R. (1995) Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes. J. Biol. Chem. 270(43), 25541-25548.
          • Soldati, T., Shapiro, A.D. and Pfeffer, S.R. (1995) Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP Dissociation Inhibitor complexes and endosome-enriched membranes. Meth. Enzym. 257, 253-259.
          • Pfeffer, S.R., Dirac-Svejstrup, A.B. and Soldati, T. (1995) Rab GDP Dissociation Inhibitor: putting Rab GTPases in the right place. J. Biol. Chem. 270(29), 17057-17059.
          • Pfeffer, S.R., Soldati, T., Geißler, H., Rancaño, C. and Dirac-Svejstrup, A.B. (1995) Selective membrane recruitment of rab GTPases. In: Cold Spring Harbour Symp., Volume LX, 221-227
          • Dirac-Svejstrup, A.B., Soldati, T., Shapiro, A.D. and Pfeffer, S.R. (1994) Rab-GDI presents functional rab9 protein to the intracellular transport machinery and contributes selectivity to rab9 membrane recruitment. J. Biol. Chem. 269(22), 15427-15430.
          • Riederer, M.A., Soldati, T., Shapiro, A.D., Lin, J. and Pfeffer, S.R. (1994) Lysosome biogenesis requires rab9 function and receptor recycling from endosomes to the trans Golgi network. J. Cell Biol. 125(3), 573-582.
          • Soldati, T., Shapiro, A.D., Dirac-Svejstrup, A.B. and Pfeffer, S.R. (1994) Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange. Nature 369, 76-78.
          • Soldati, T., Riederer, M. A. and Pfeffer, S. R. (1993) Rab-GDI, a solubilizing and recycling factor for rab9 protein. Mol. Biol. Cell 4 (4), 425-434.
          • Lombardi, D., Soldati, T., Riederer, M. A., Goda, Y., Zerial, M. and Pfeffer, S. R. (1993) Rab9 functions in transport between late endosomes and the trans Golgi network. EMBO J. 12 (2), 677-682.
          • Goda, Y., Soldati, T. and Pfeffer, S. R. (1992) Transport from late endosomes to the trans Golgi network in semi intact cell extracts. Meth. Enzym., 219, 153-159.
          • Perriard, J.-C., von Arx, P., Bantle, S., Eppenberger, H.M., Eppenberger-Eberhardt, M., Messerli, M. and Soldati, T. (1992) Molecular analysis of protein sorting during biogenesis of muscle cytoarchitecture. Symp. Soc. Exp. Biol., 46, 219-235.
          • Soldati, T. and Perriard, J.-C. (1991) Intracompartmental sorting of essential myosin light chains: molecular dissection and in vivo monitoring by epitope tagging. Cell 66, 277-289.
          • Wirz, T., U. Brändle, Soldati,T., Hossle, J.P. and Perriard, J.-C. (1990) A unique chicken B-creatine kinase gene gives rise to two B-creatine kinase isoproteins with distinct N-termini by alternative splicing. J. Biol. Chem. 265, 11656-11666.
          • Quest, A.F., Soldati, T., Hemmer, W., Perriard, J.-C., Eppenberger, H.M. and Wallimann, T. (1990) Phosphorylation of chicken brain-type creatine kinase affects a physiologically important kinetic parameter and gives rise to protein microheterogeneity in vivo. FEBS Lett. 269, (2), 457-464.
          • Soldati, T., Schäfer, B.W. and Perriard, J.-C. (1990) Alternative ribosomal initiation gives rise to chicken brain-type creatine kinase isoproteins with different amino termini. J. Biol. Chem. 265, 4498-4506.
          • Perriard, J.-C., Hossle, J.P., Schäfer, B.W., Soldati, T., Wegmann, G. and Wirz, T. (1988) Multiple tasks of creatine kinase isoproteins. Cellular and Molecular Biology of Muscle Development, 545-554.