- Lewis Acid / CpRu Dual Catalysis in the Enantioselective Decarboxylative Allylation of Ketone Enolates
David Linder, Martina Austeri, Jérôme Lacour
Org. Biomol. Chem. 2009, 7, 4057-4061
The addition of a Lewis acidic metal triflate salt Mg(OTf)2 as co-catalyst in the CpRu-catalyzed decarboxylative allylation of in situ-generated ketone enolates allows the reaction to proceed at lower temperature with higher regio- and enantioselectivity. Even so-far-unreactive substrates react.
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