173. New Biphenyl Iminium Salt Catalysts for Highly Enantioselective Asymmetric Epoxidation: Role of Additional Substitution and Dihedral Angle.
     Philip Charles Bulman Page, Christopher Bartlett, Yohan Chan, Steve Allin, Michael McKenzie, Jérôme Lacour, Garth Jones
     Org. Biomol. Chem. 2016, 14, 4220-4232

New biaryl iminium salt catalysts for enantioselective alkene epoxidation containing additional substitution in the heterocyclic ring are reported. The effects upon conformation and enantioselectivity of this additional substitution, and the correlation with dihedral angle in these systems, has been investigated using a synthetic approach supported by density functional theory. Enantioselectivities of up to 97% ee were observed.

DOI : 10.1039/C6OB00542J 

archive ouverte unige:83546