33. α-Arylation, α-Arylative Esterification, or Acylation: A Stoichiometry-Dependent Trichotomy in the Pd-Catalyzed Cross-Coupling between Aldehydes and Aryl Bromides
    Pradeep Nareddy, Clément Mazet*
    Chem. Asian J. 2013, 8, 2579-2583

The selective α-arylation and α-arylative esterification of linear and branched aldehydes is reported for a variety of bromoarenes. The acylation of aryl bromides can be achieved with linear aldehydes (see scheme). All these transformations were performed with a single [(N-heterocyclic carbene)Pd] catalyst through adjustment of the stoichiometry of the reagents and the appropriate base.

archive ouverte unige:30785

DOI de la version éditeur : 10.1002/asia.201300724