Projects

NSCLBP Project

NSCLBP Project

Title Identifying Subgroups of Patients With Chronic Nonspecific Low Back Pain Based on a Multifactorial Approach
Dates Since 2016
Principal investigator Kevin Rose-Dulcina (UNIGE/HUG)
Other investigators Stéphane Genevay (HUG), Stéphane Armand (K-Lab, UNIGE/HUG), Florent Moissenet (K-Lab, UNIGE/HUG)
Institutional collaborations AGEIS, University of Grenoble-Alpes, Grenoble, France (Nicholas Vuillerme)
Funding The French National Research Agency in the framework of the “Investissements d’Avenir” program (ANR-10-AIRT-05 and ANR-15-IDEX-02)
Keywords Non-specific chronic low back pain; activities of daily living; psychology; electromyography; classification
Website Not available.
Related articles
  • Not available

Abstract

Low back pain, especially nonspecific chronic low back pain (LBP), the leading cause of disability worldwide, represents both social and economic problems. Different therapeutic management techniques can be used, but their effects vary. Clinicians and researchers attribute the variation in the efficacy of therapeutic and management techniques to the heterogeneity of the nonspecific chronic LBP population, and they agree that nonspecific chronic LBP must be subgrouped. This project aims to identify nonspecific chronic LBP subgroups based on a multifactorial approach, including biomechanical, physical, and psychosocial data. A total of 100 nonspecific chronic LBP patients and 30 healthy participants aged between 18 and 60 years will be recruited for this study. A psychosocial profile and physical capacity evaluation will be established. The subjects will perform functional daily life activities with full body kinematics, kinetics, and surface electromyography of the trunk and hip muscles assessed. The clustering classification methods for the statistical analysis will be determined according to the data and will be used to identify the subgroups of nonspecific chronic LBP patients. Identifying subgroups with a multifactorial approach is more comprehensive and closer to the pathophysiology of nonspecific chronic LBP. The study’s results are expected to support clinicians for a more adapted therapeutic management for each subgroup.