Faculté de médecine Faculté de médecine

BioCode: RNA to proteins (R2P) Platform analyzes gene expression at the level of translation

  • We provide analysis of translatome by polysome fractionation and Ribo-Seq (differential translation, translation efficiency, RNA translatability, ribosome pausing, etc). We also perform in vitro translation in cell-free protein system and analysis of protein solubility

  • We are working with different organisms and tissue cultures: bacteria, pathogens, yeast, mammalian cells and tissues...

  • We provide consulting, assistance and technical advice to help researcher in experiments design.

  • Our Facility is dedicated to local academic users (University of Geneva) but is also open for external academic researchers and for industry.

 

 

The main activities of R2P platform:

  • Ribosome isolation and fractionation

  • Analysis of translatome by Ribo-Seq (Ribosome profiling)

  • Cryogenic Disruption

  • Analysis of protein solubility

  • Isolation of soluble and aggregated proteins

  • Density gradient centrifugation

  • In vitro translation