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Publication 211
- Towards the Asymmetric Synthesis of Ascochlorin
Dogan, Ö.; Oppolzer, W.
Turk. J. Chem. 2001, 25, 273-281
A synthetic approach is described to the asymmetric synthesis of ascochlorin (1), an antiviral antibiotic, based on the construction of a sesquiterpene unit via asymmetric Diels-Alder reaction of tigloyl sultam 4 & butadiene, and the introduction of the aromatic side chain (C9-C12 unit) by employing cuprate chemistry.
Lien : http://journals.tubitak.gov.tr/chem/abstract.htm?id=4676