- Reversible Anticoagulants: Inspired by Nature, Designed for Safety
Dockerill, M.; Winssinger, N.
The Science Breaker 2024, 10
Upon biting, blood sucking insects inject an anti-coagulant to enjoy their meal. These anti-coagulants have inspired approved drug. Combining this concept with supramolecular chemistry, we developed a novel bi-functional drug. It shows strong in vivo effects and can be reversed with an 'antidote,' a sought-after trait in anti-coagulant treatments. This property extends to other therapies like immunotherapies, broadening its potential impact on diverse medical applications.
DOI : 10.25250/thescbr.brk786
