Publication 349

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  1. Assies, L.; García-Calvo, J.; Piazzolla, F.; Sanchez, S.; Kato, T.; Reymond, L.; Goujon, A.; Colom, A.; López-Andarias, J.; Straková, K.; Mahecic, D.; Mercier, V.; Riggi, M.; Jiménez-Rojo, N.; Roffay, C.; Licari, G.; Tsemperouli, M.; Neuhaus, F.; Fürstenberg, A.; Vauthey, E.; Hoogendoorn, S.; Gonzalez-Gaitan, M.; Zumbuehl, A.; Sugihara, K.; Gruenberg, J.; Riezman, H.; Loewith, R.; Manley, S.; Roux, A.; Winssinger, N.; Sakai, N.; Pitsch, S.; Matile, S. “Flipper Probes for the Community” Chimia 2021, 75, 1004-1011

This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR®, ER Flipper-TR®, Lyso Flipper-TR®, and Mito Flipper-TR®. They are available from Spirochrome.

DOI: 10.2533/chimia.2021.1004 

open archive unige:157671 • pdf