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Publication 54
- Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents
D. García-Cuadrado, S. Barluenga, N. Winssinger
Chem. Commun. 2008, 4619-4621
A concise sequence utilizing a Petasis three component reaction followed by a tandem aza-Cope-Mannich cyclization afforded novel polycyclic heterocycles in good yield; alternative iminium cyclization based on a Pictet-Spengler reaction or aminal formation led to divergent pathways affording skeletal diversity.
DOI : 10.1039/B807869F
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