223. R. Millet, A. Alexakis,
     “Copper-catalyzed kinetic resolution of 1,3-cyclohexadiene monoepoxide with Grignard reagents”
     Synlett 2007, 435-438.

Chiral ferrocenyl-based diphosphines lead to kinetic ­resolution of 1,3-cyclohexadiene monoepoxide with moderate to good enantioselectivity (up to 90% ee) and good regioselectivity with various Grignard reagents through an anti-S_N2′ pathway.

DOI : 10.1055/s-2007-967945 

archive ouverte unige:8027