253. R. Millet, T. Bernardez, L. Palais, A. Alexakis,
     “Copper-catalyzed desymmetrization of oxabenzonorbornadienes with aluminum reagents”
     Tetrahedron Lett. 2009, 50, 3474-3477.

The desymmetrization of oxabenzonorbornadienes with aluminum reagents and SimplePhos as chiral ligand is described. The corresponding homoallylic alcohols are obtained in high yield, diastereoselectivity, and enantiomeric excess. Furthermore the first anti enantioselective desymmetrization with aromatic nucleophiles is reported.

DOI : 10.1016/j.tetlet.2009.02.219 

archive ouverte unige:8478