288. J.-B. Langlois, A. Alexakis,
     “Identification of a Valuable Kinetic Process in Copper-Catalyzed Asymmetric Allylic Alkylation”
     Angew. Chem. Int. Ed. 2011, 50, 1877-1881.

Copper bottomed: The application of a previously described process of dynamic kinetic asymmetric transformation to acyclic substrates allowed the identification of a relevant kinetic process in the title reaction (see scheme; CuTC= copper(I) thiophencarboxylate, Naphth= naphthyl). The optimization of the reaction conditions and generality of the method, as well as mechanistic considerations are disclosed.

DOI : 10.1002/anie.201005373 

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