293. A. Quintard, A. Alexakis,
     “Highly enantioselective organocascade intermolecular iminium/enamine Michael addition on enals”
     Chem. Commun. 2011, 47, 7212-7214.

An unprecedented intermolecular iminium/enamine Michael addition on enals has been developed by taking advantage of the high reactivity of vinyl sulfones. This powerful organocascade allows for the rapid construction of attractive synthons in high enantioselectivities (typically 99% ee).

DOI : 10.1039/C1CC11967B 

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