11. Dinuclear {(salen)Al} Complexes Display Expanded Scope in the Conjugate Cyanation of α,β-Unsaturated Imides
    Clément Mazet, Eric N. Jacobsen*
    Angew. Chem. Int. Ed. 2008, 47, 1762-1765
    [ Highlighted in: Synfacts 2008, 487 ]

Al together: Covalently linked dinuclear {(salen)Al} complexes catalyze the conjugate cyanation of α,β-unsaturated imides with several orders of magnitude greater reactivity over the mononuclear analogue, and with comparable enantioselectivity. Imides that were completely unreactive with homo- and heterobimetallic combinations of mononuclear catalysts can now be converted into the corresponding cyanation products with high enantiomeric excess.

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DOI de la version éditeur : 10.1002/anie.200704461